ELK3 (ETS transcription factor ELK3)

2003-02-01  

Identity

HGNC
ELK3
LOCATION
12q23.1
LOCUSID
2004
ALIAS
ERP,NET,SAP-2,SAP2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2004
MIM: 600247
HGNC: 3325
Ensembl: ENSG00000111145

Variants:

dbSNP: 2004
ClinVar: 2004
TCGA: ENSG00000111145
COSMIC: ELK3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111145ENST00000228741P41970
ENSG00000111145ENST00000228741A0A024RBE2
ENSG00000111145ENST00000547249F8VZQ0
ENSG00000111145ENST00000547860F8VUJ0
ENSG00000111145ENST00000549985H0YIH6
ENSG00000111145ENST00000552142G3V1Z7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386322442024ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance.0
386322442024ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance.0
369502182023ELK3-CXCL16 axis determines natural killer cell cytotoxicity via the chemotactic activity of CXCL16 in triple negative breast cancer.1
373946392023ELK3 Targeting AEG1 Promotes Migration and Invasion of Ovarian Cancer Cells under Hypoxia.1
375428632023ETS transcription factor ELK3 in human cancers: An emerging therapeutic target.1
381886752023ELK3-ID4 axis governs the metastatic features of triple negative breast cancer.0
369502182023ELK3-CXCL16 axis determines natural killer cell cytotoxicity via the chemotactic activity of CXCL16 in triple negative breast cancer.1
373946392023ELK3 Targeting AEG1 Promotes Migration and Invasion of Ovarian Cancer Cells under Hypoxia.1
375428632023ETS transcription factor ELK3 in human cancers: An emerging therapeutic target.1
381886752023ELK3-ID4 axis governs the metastatic features of triple negative breast cancer.0
354090692022ELK3 Controls Gastric Cancer Cell Migration and Invasion by Regulating ECM Remodeling-Related Genes.11
359052572022Molecular and clinical features of a potential immunotherapy target ELK3 in glioma.1
362438652022Circular RNA hsa_circ_0000144 aggravates ovarian Cancer progression by regulating ELK3 via sponging miR-610.1
363281942022Deubiquitinase UCHL5 stabilizes ELK3 to potentiate cancer stemness and tumor progression in pancreatic adenocarcinoma (PAAD).9
354090692022ELK3 Controls Gastric Cancer Cell Migration and Invasion by Regulating ECM Remodeling-Related Genes.11

Citation

Dessen P

ELK3 (ETS transcription factor ELK3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40443/meetings/css/lib/cancer-prone-explorer/favicon/manifest.json