EMX2 (empty spiracles homeobox 2)

2003-02-01  

Identity

HGNC
EMX2
LOCATION
10q26.11
LOCUSID
2018
ALIAS
-

Other Information

Locus ID:

NCBI: 2018
MIM: 600035
HGNC: 3341
Ensembl: ENSG00000170370

Variants:

dbSNP: 2018
ClinVar: 2018
TCGA: ENSG00000170370
COSMIC: EMX2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170370ENST00000442245Q04743
ENSG00000170370ENST00000553456Q04743
ENSG00000170370ENST00000616794A0A087WWJ6

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383628402024EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway.0
383628402024EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway.0
358186362023Spatial control of astrogenesis progression by cortical arealization genes.1
358186362023Spatial control of astrogenesis progression by cortical arealization genes.1
340169582021Regulation of sarcomagenesis by the empty spiracles homeobox genes EMX1 and EMX2.10
343643912021Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis.6
340169582021Regulation of sarcomagenesis by the empty spiracles homeobox genes EMX1 and EMX2.10
343643912021Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis.6
304507752019Wnt and BMP signaling pathways co-operatively induce the differentiation of multiple myeloma mesenchymal stem cells into osteoblasts by upregulating EMX2.15
316710932019A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing.12
304507752019Wnt and BMP signaling pathways co-operatively induce the differentiation of multiple myeloma mesenchymal stem cells into osteoblasts by upregulating EMX2.15
316710932019A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing.12
305763382018The downregulation of lncRNA EMX2OS might independently predict shorter recurrence-free survival of classical papillary thyroid cancer.16
305763382018The downregulation of lncRNA EMX2OS might independently predict shorter recurrence-free survival of classical papillary thyroid cancer.16
277126002017Empty Spiracles Homeobox 2 (EMX2) Inhibits the Invasion and Tumorigenesis in Colorectal Cancer Cells.4

Citation

Dessen P

EMX2 (empty spiracles homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40449/case-report-explorer/tumors-explorer/css/humanGenome