FGF13 (fibroblast growth factor 13)

2003-02-01  

Identity

HGNC
FGF13
LOCATION
Xq26.3
LOCUSID
2258
ALIAS
DEE90,FGF-13,FGF2,FHF-2,FHF2,LINC00889

Other Information

Locus ID:

NCBI: 2258
MIM: 300070
HGNC: 3670
Ensembl: ENSG00000129682

Variants:

dbSNP: 2258
ClinVar: 2258
TCGA: ENSG00000129682
COSMIC: FGF13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129682ENST00000305414Q92913
ENSG00000129682ENST00000315930Q92913
ENSG00000129682ENST00000315930A8K1P5
ENSG00000129682ENST00000421460A0A0C4DG13
ENSG00000129682ENST00000436198Q92913
ENSG00000129682ENST00000441825Q92913
ENSG00000129682ENST00000448673B1B1H9
ENSG00000129682ENST00000455663B1AJW0
ENSG00000129682ENST00000626909Q92913

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
Regulation of actin cytoskeletonKEGGko04810
MelanomaKEGGko05218
MAPK signaling pathwayKEGGhsa04010
Regulation of actin cytoskeletonKEGGhsa04810
Pathways in cancerKEGGhsa05200
MelanomaKEGGhsa05218
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Ras signaling pathwayKEGGhsa04014
Rap1 signaling pathwayKEGGhsa04015
Rap1 signaling pathwayKEGGko04015
Muscle contractionREACTOMER-HSA-397014
Cardiac conductionREACTOMER-HSA-5576891
Phase 0 - rapid depolarisationREACTOMER-HSA-5576892
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

References

Pubmed IDYearTitleCitations
387333102024FGF13 enhances the function of TRPV1 by stabilizing microtubules and regulates acute and chronic itch.0
387333102024FGF13 enhances the function of TRPV1 by stabilizing microtubules and regulates acute and chronic itch.0
369884032023The inhibitory role of microRNA-141-3p in human cutaneous melanoma growth and metastasis through the fibroblast growth factor 13-mediated mitogen-activated protein kinase axis.0
375362932023A Heterozygous Variant of FGF13 Caused X-Linked Developmental and Epileptic Encephalopathy 90 in a Chinese Family.0
376039672023FGF13A interacts with NPM1 and UBF and inhibits the invasion of bladder cancer cells.0
369884032023The inhibitory role of microRNA-141-3p in human cutaneous melanoma growth and metastasis through the fibroblast growth factor 13-mediated mitogen-activated protein kinase axis.0
375362932023A Heterozygous Variant of FGF13 Caused X-Linked Developmental and Epileptic Encephalopathy 90 in a Chinese Family.0
376039672023FGF13A interacts with NPM1 and UBF and inhibits the invasion of bladder cancer cells.0
348717842022Further evidence of affected females with a heterozygous variant in FGF13 causing X-linked developmental and epileptic encephalopathy 90.4
360534112022FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches.1
348717842022Further evidence of affected females with a heterozygous variant in FGF13 causing X-linked developmental and epileptic encephalopathy 90.4
360534112022FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches.1
332458602021Missense variants in the N-terminal domain of the A isoform of FHF2/FGF13 cause an X-linked developmental and epileptic encephalopathy.10
332852622021Increased expression of fibroblast growth factor 13 in cortical lesions of the focal cortical dysplasia.0
334923802021FGF10 and FGF13 genetic variation and tooth-size discrepancies.1

Citation

Dessen P

FGF13 (fibroblast growth factor 13)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40553/gene-fusions-explorer/haematological-explorer/cancer-prone-explorer/