FZD9 (frizzled class receptor 9)

2003-06-01 Affiliation

Identity

HGNC

FZD9

LOCATION

7q11.23

LOCUSID

8326

ALIAS

CD349,FZD3

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 8326
MIM: 601766
HGNC: 4047
Ensembl: ENSG00000188763

Variants:

dbSNP: 8326
ClinVar: 8326
TCGA: ENSG00000188763
COSMIC: FZD9

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000188763	ENST00000344575	O00144

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
mTOR signaling pathway	KEGG	ko04150
Wnt signaling pathway	KEGG	ko04310
Melanogenesis	KEGG	ko04916
Basal cell carcinoma	KEGG	ko05217
mTOR signaling pathway	KEGG	hsa04150
Wnt signaling pathway	KEGG	hsa04310
Melanogenesis	KEGG	hsa04916
Pathways in cancer	KEGG	hsa05200
Basal cell carcinoma	KEGG	hsa05217
HTLV-I infection	KEGG	ko05166
HTLV-I infection	KEGG	hsa05166
Hippo signaling pathway	KEGG	hsa04390
Hippo signaling pathway	KEGG	ko04390
Proteoglycans in cancer	KEGG	hsa05205
Proteoglycans in cancer	KEGG	ko05205
Signaling pathways regulating pluripotency of stem cells	KEGG	hsa04550
Signaling pathways regulating pluripotency of stem cells	KEGG	ko04550
Wnt signaling	KEGG	hsa_M00677
Wnt signaling	KEGG	M00677
Signal Transduction	REACTOME	R-HSA-162582
Signaling by GPCR	REACTOME	R-HSA-372790
GPCR ligand binding	REACTOME	R-HSA-500792
Class B/2 (Secretin family receptors)	REACTOME	R-HSA-373080
Breast cancer	KEGG	ko05224
Breast cancer	KEGG	hsa05224

References

Pubmed ID	Year	Title	Citations
35149732	2022	miR-520a-5p regulates Frizzled 9 expression and mediates effects of cigarette smoke and iloprost chemoprevention.	5
35149732	2022	miR-520a-5p regulates Frizzled 9 expression and mediates effects of cigarette smoke and iloprost chemoprevention.	5
28665975	2017	Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9.	29
28665975	2017	Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9.	29
27314612	2016	Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia.	7
27314612	2016	Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia.	7
20398908	2010	Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.	34
20458727	2010	Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells.	35
20501643	2010	Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.	48
20398908	2010	Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.	34
20458727	2010	Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells.	35
20501643	2010	Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.	48
18832655	2009	Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.	154
19038973	2009	Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells.	22
19543507	2009	Non-association between polymorphisms of the frizzled receptor genes and bone mineral density in postmenopausal Korean women.	2

Citation

Dessen P

FZD9 (frizzled class receptor 9)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40659/js/teaching-explorer/