GGT1 (gamma-glutamyltransferase 1)

2003-06-01  

Identity

HGNC
GGT1
LOCATION
22q11.23
LOCUSID
2678
ALIAS
CD224,D22S672,D22S732,GGT,GGT
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2678
MIM: 612346
HGNC: 4250
Ensembl: ENSG00000286070

Variants:

dbSNP: 2678
ClinVar: 2678
TCGA: ENSG00000286070
COSMIC: GGT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000286070ENST00000248923P19440
ENSG00000286070ENST00000248923A0A140VJJ9
ENSG00000286070ENST00000439775H3BT13

Pathways

PathwaySourceExternal ID
Taurine and hypotaurine metabolismKEGGko00430
Glutathione metabolismKEGGko00480
Arachidonic acid metabolismKEGGko00590
Taurine and hypotaurine metabolismKEGGhsa00430
Glutathione metabolismKEGGhsa00480
Arachidonic acid metabolismKEGGhsa00590
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Arachidonic acid metabolismREACTOMER-HSA-2142753
Synthesis of Leukotrienes (LT) and Eoxins (EX)REACTOMER-HSA-2142691
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Glutathione conjugationREACTOMER-HSA-156590
Glutathione synthesis and recyclingREACTOMER-HSA-174403
Aflatoxin activation and detoxificationREACTOMER-HSA-5423646

References

Pubmed IDYearTitleCitations
383770672024The importance of the enzyme Gamma-glutamyltransferase in the pathogenic cluster in type2 diabetic patient.0
385227562024The discovery of GGT1 as a novel gene for ischemic stroke conferring protection against disease risk in non-smokers and non-abusers of alcohol.0
388065292024GGT1 is a SNP eQTL gene involved in STAT3 activation and associated with the development of Post-ERCP pancreatitis.0
383770672024The importance of the enzyme Gamma-glutamyltransferase in the pathogenic cluster in type2 diabetic patient.0
385227562024The discovery of GGT1 as a novel gene for ischemic stroke conferring protection against disease risk in non-smokers and non-abusers of alcohol.0
388065292024GGT1 is a SNP eQTL gene involved in STAT3 activation and associated with the development of Post-ERCP pancreatitis.0
365860742023Relationship between slow-wave sleep and serum γ-glutamine transaminase in non-obese men with obstructive sleep apnea-hypopnea syndrome.1
366300692023The relationship between serum γ-glutamyltransferase (GGT) and diabetic nephropathy in patients with type 2 diabetes mellitus: a cross-sectional study.1
368781972023Serum Inflammation Parameters and Survival in Hepatocellular Carcinoma Patients: Importance of Albumin and Gamma-Glutamyltranspeptidase.2
372673862023Association of gamma-glutamyl transferase variability with risk of osteoporotic fractures: A nationwide cohort study.5
376123042023Association between the accumulation of elevated serum γ-glutamyltransferase level and risk of atrial fibrillation: a nationwide cohort study.0
379044802023Clinical application value of hepatitis B virus basal core promoter 1762/1764 and GGTII and GGT in patients with HBV-DNA-positive primary liver cancer.0
380022742023Potential Causal Association between Elevated Gamma-Glutamyl Transferase Level and Stroke: A Two-Sample Mendelian Randomization Study.1
380728552023Higher gamma-glutamyl transferase levels are associated with an increased risk of incident systemic sclerosis: a nationwide population-based study.0
365860742023Relationship between slow-wave sleep and serum γ-glutamine transaminase in non-obese men with obstructive sleep apnea-hypopnea syndrome.1

Citation

Dessen P

GGT1 (gamma-glutamyltransferase 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40709/js/lib/favicon/deep-insight-explorer/