IER2 (immediate early response 2)

2003-12-01  

Identity

HGNC
IER2
LOCATION
19p13.13
LOCUSID
9592
ALIAS
ETR101
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9592
HGNC: 28871
Ensembl: ENSG00000160888

Variants:

dbSNP: 9592
ClinVar: 9592
TCGA: ENSG00000160888
COSMIC: IER2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160888ENST00000292433Q9BTL4
ENSG00000160888ENST00000292433A0A024R7H1
ENSG00000160888ENST00000587885Q9BTL4
ENSG00000160888ENST00000587885A0A024R7H1
ENSG00000160888ENST00000588173Q9BTL4
ENSG00000160888ENST00000588173A0A024R7H1

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
360475622023PP2A-B55 and its adapter proteins IER2 and IER5 regulate the activity of RB family proteins and the expression of cell cycle-related genes.4
360475622023PP2A-B55 and its adapter proteins IER2 and IER5 regulate the activity of RB family proteins and the expression of cell cycle-related genes.4
360179182022Long Non-Coding RNA PCAT19 Regulates the Malignant Progression of Bladder Cancer through the miR-335-5p/IER2 Axis.1
360179182022Long Non-Coding RNA PCAT19 Regulates the Malignant Progression of Bladder Cancer through the miR-335-5p/IER2 Axis.1
346113092021IER2-induced senescence drives melanoma invasion through osteopontin.9
346113092021IER2-induced senescence drives melanoma invasion through osteopontin.9
320094202020Immediate early response protein 2 promotes the migration and invasion of hepatocellular carcinoma cells via regulating the activity of Rho GTPases.5
320094202020Immediate early response protein 2 promotes the migration and invasion of hepatocellular carcinoma cells via regulating the activity of Rho GTPases.5
305992132019IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A.6
305992132019IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A.6
278409692017Immediate early response protein 2 regulates hepatocellular carcinoma cell adhesion and motility via integrin β1-mediated signaling pathway.10
278409692017Immediate early response protein 2 regulates hepatocellular carcinoma cell adhesion and motility via integrin β1-mediated signaling pathway.10
262601372015Identification of immediate early response protein 2 as a regulator of angiogenesis through the modulation of endothelial cell motility and adhesion.9
262601372015Identification of immediate early response protein 2 as a regulator of angiogenesis through the modulation of endothelial cell motility and adhesion.9
221207132012The immediate early gene Ier2 promotes tumor cell motility and metastasis, and predicts poor survival of colorectal cancer patients.22

Citation

Dessen P

IER2 (immediate early response 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40918/cancer-prone-explorer/js/humanGenome