JTB (jumping translocation breakpoint)

2003-02-01  

Identity

HGNC
JTB
LOCATION
1q21.3
LOCUSID
10899
ALIAS
HJTB,HSPC222,PAR,hJT
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10899
MIM: 604671
HGNC: 6201
Ensembl: ENSG00000143543

Variants:

dbSNP: 10899
ClinVar: 10899
TCGA: ENSG00000143543
COSMIC: JTB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143543ENST00000271843O76095
ENSG00000143543ENST00000356648O76095
ENSG00000143543ENST00000368589O76095
ENSG00000143543ENST00000428469O76095

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
220790492012The structure of the extracellular domain of the jumping translocation breakpoint protein reveals a variation of the midkine fold.3
232974972012[Downregulation of PAR expression induces the apoptosis of human prostate cancer PC3 cells and increases the Bcl-2/Bax ratio].1
220790492012The structure of the extracellular domain of the jumping translocation breakpoint protein reveals a variation of the midkine fold.3
232974972012[Downregulation of PAR expression induces the apoptosis of human prostate cancer PC3 cells and increases the Bcl-2/Bax ratio].1
212252292011PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins.7
212252292011PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins.7
194870722009Interacting with HBsAg compromises resistance of jumping translocation breakpoint protein to ultraviolet radiation-induced apoptosis in 293FT cells.5
194870722009Interacting with HBsAg compromises resistance of jumping translocation breakpoint protein to ultraviolet radiation-induced apoptosis in 293FT cells.5
125862952003Positional mapping for amplified DNA sequences on 1q21-q22 in hepatocellular carcinoma indicates candidate genes over-expression.33
125862952003Positional mapping for amplified DNA sequences on 1q21-q22 in hepatocellular carcinoma indicates candidate genes over-expression.33

Citation

Dessen P

JTB (jumping translocation breakpoint)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41044/js/lib/favicon/case-report-explorer/