KLF12 (Kruppel like factor 12)

2003-06-01  

Identity

HGNC
LOCATION
13q22.1
LOCUSID
ALIAS
AP-2rep,AP2REP,HSPC122
FUSION GENES

Other Information

Locus ID:

NCBI: 11278
MIM: 607531
HGNC: 6346
Ensembl: ENSG00000118922

Variants:

dbSNP: 11278
ClinVar: 11278
TCGA: ENSG00000118922
COSMIC: KLF12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118922ENST00000377669Q9Y4X4

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371567742023KLF12 promotes the proliferation of breast cancer cells by reducing the transcription of p21 in a p53-dependent and p53-independent manner.3
372901722023MiR-17-5p promoter methylation regulated by DNA methyltransferase 3 beta (DNMT3B) expedites endometriosis via the Krüppel-like factor 12 (KLF12)/Wnt/β-catenin axis.1
375433622023Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production.0
376065302023KLF12 transcriptionally regulates PD-L1 expression in non-small cell lung cancer.0
376982632023Circ_0084188 promotes colorectal cancer progression by sponging miR-654-3p and regulating kruppel-like factor 12.1
371567742023KLF12 promotes the proliferation of breast cancer cells by reducing the transcription of p21 in a p53-dependent and p53-independent manner.3
372901722023MiR-17-5p promoter methylation regulated by DNA methyltransferase 3 beta (DNMT3B) expedites endometriosis via the Krüppel-like factor 12 (KLF12)/Wnt/β-catenin axis.1
375433622023Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production.0
376065302023KLF12 transcriptionally regulates PD-L1 expression in non-small cell lung cancer.0
376982632023Circ_0084188 promotes colorectal cancer progression by sponging miR-654-3p and regulating kruppel-like factor 12.1
362721522022MicroRNA-650 suppresses KLF12 expression to regulate growth and metastasis of human ovarian cancer cells.2
362721522022MicroRNA-650 suppresses KLF12 expression to regulate growth and metastasis of human ovarian cancer cells.2
332796282021Krüppel-like factor 12 suppresses bladder cancer growth through transcriptionally inhibition of enolase 2.10
341175892021Knockdown of circ_0075503 suppresses cell migration and invasion by regulating miR-15a-5p and KLF12 in endometriosis.5
344619262021Circ-RNF111 aggravates the malignancy of gastric cancer through miR-876-3p-dependent regulation of KLF12.9

Citation

Dessen P

KLF12 (Kruppel like factor 12)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41073/js/js/lib/gene-explorer/