KRT19 (keratin 19)

2003-08-01  

Identity

HGNC
KRT19
LOCATION
17q21.2
LOCUSID
3880
ALIAS
CK19,K19,K1CS
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3880
MIM: 148020
HGNC: 6436
Ensembl: ENSG00000171345

Variants:

dbSNP: 3880
ClinVar: 3880
TCGA: ENSG00000171345
COSMIC: KRT19

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171345ENST00000361566P08727
ENSG00000171345ENST00000455635C9JM50
ENSG00000171345ENST00000593096K7EMS3

Expression (GTEx)

0
500
1000
1500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
KeratinizationREACTOMER-HSA-6805567

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368255812023Keratin19 promotes pancreatic cancer progression and poor prognosis via activating the Hedgehog pathway.0
373121992023Combination of CEACAM5, EpCAM and CK19 gene expressions in mediastinal lymph node micrometastasis is a prognostic factor for non-small cell lung cancer.1
373874402023Clinical implications of Cytokeratin 19 expression in patients with oral squamous cell carcinoma.0
375553622023DNA methylation-associated allelic inactivation regulates Keratin 19 gene expression during pancreatic development and carcinogenesis.0
375922562023Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer.1
368255812023Keratin19 promotes pancreatic cancer progression and poor prognosis via activating the Hedgehog pathway.0
373121992023Combination of CEACAM5, EpCAM and CK19 gene expressions in mediastinal lymph node micrometastasis is a prognostic factor for non-small cell lung cancer.1
373874402023Clinical implications of Cytokeratin 19 expression in patients with oral squamous cell carcinoma.0
375553622023DNA methylation-associated allelic inactivation regulates Keratin 19 gene expression during pancreatic development and carcinogenesis.0
375922562023Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer.1
334950322022Diagnostic utility of LDH, CA125 and CYFRA21-1 in tuberculosis pleural effusion.4
349697692022Establishment of Patient-derived Preclinical Models for Invasive Papillary Cholangiocarcinoma.1
352789792022Differentiating Cytokeratin 19 expression of hepatocellular carcinoma by using multi-b-value diffusion-weighted MR imaging with mono-exponential, stretched exponential, intravoxel incoherent motion, diffusion kurtosis imaging and fractional order calculus models.8
356797112022Dysregulation of KRT19, TIMP1, and CLDN1 gene expression is associated with thyroid cancer.1
357254702022Individual and joint influence of cytokeratin 19 and microvascular invasion on the prognosis of patients with hepatocellular carcinoma after hepatectomy.2

Citation

Dessen P

KRT19 (keratin 19)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/41105/deep-insight-explorer/js/lib/gene-explorer/