LAMP3 (lysosomal associated membrane protein 3)

2003-02-01  

Identity

HGNC
LAMP3
LOCATION
3q27.1
LOCUSID
27074
ALIAS
CD208,DC
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27074
MIM: 605883
HGNC: 14582
Ensembl: ENSG00000078081

Variants:

dbSNP: 27074
ClinVar: 27074
TCGA: ENSG00000078081
COSMIC: LAMP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000078081ENST00000265598Q9UQV4
ENSG00000078081ENST00000466939E7ETP9
ENSG00000078081ENST00000470251C9JDI8
ENSG00000078081ENST00000476015C9JYP5

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382175442024LAMP3 is a potent uterine corpus endometrial carcinoma prognostic biomarker associated with immune behavior.1
383307302024The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets.0
382175442024LAMP3 is a potent uterine corpus endometrial carcinoma prognostic biomarker associated with immune behavior.1
383307302024The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets.0
367882552023LAMP3 transfer via extracellular particles induces apoptosis in Sjögren's disease.0
370965702023Lysosome-Associated Membrane Protein 3 Induces Lysosome-Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease.2
377406562023MiR-526b-3p enhances sensitivity of head and neck squamous cell carcinoma cells to radiotherapy via suppressing exosomal LAMP3-mediated autophagy.0
378788842023Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells.1
367882552023LAMP3 transfer via extracellular particles induces apoptosis in Sjögren's disease.0
370965702023Lysosome-Associated Membrane Protein 3 Induces Lysosome-Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease.2
377406562023MiR-526b-3p enhances sensitivity of head and neck squamous cell carcinoma cells to radiotherapy via suppressing exosomal LAMP3-mediated autophagy.0
378788842023Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells.1
348023792022LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization.20
363501532022LAMP3/CD63 Expression in Early and Late Endosomes in Human Vaginal Epithelial Cells Is Associated with Enhancement of HSV-2 Infection.1
363778732022Upregulation of ATF4-LAMP3 Axis by ORF45 Facilitates Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.2

Citation

Dessen P

LAMP3 (lysosomal associated membrane protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41123/css/lib/favicon/tumors-explorer/