MOS (MOS proto-oncogene, serine/threonine kinase)

2003-02-01  

Identity

HGNC
MOS
LOCATION
8q12.1
LOCUSID
4342
ALIAS
MSV

Other Information

Locus ID:

NCBI: 4342
MIM: 190060
HGNC: 7199
Ensembl: ENSG00000172680

Variants:

dbSNP: 4342
ClinVar: 4342
TCGA: ENSG00000172680
COSMIC: MOS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172680ENST00000311923P00540

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
Regulation of actin cytoskeletonKEGGko04810
Progesterone-mediated oocyte maturationKEGGko04914
MAPK signaling pathwayKEGGhsa04010
Regulation of actin cytoskeletonKEGGhsa04810
Progesterone-mediated oocyte maturationKEGGhsa04914
Oocyte meiosisKEGGko04114
Oocyte meiosisKEGGhsa04114
MAPK (ERK1/2) signalingKEGGhsa_M00687
MAPK (ERK1/2) signalingKEGGM00687

References

Pubmed IDYearTitleCitations
364036232022MOS mutation causes female infertility with large polar body oocytes.1
364036232022MOS mutation causes female infertility with large polar body oocytes.1
255125302014Genetic modifiers of EGFR dependence in non-small cell lung cancer.36
255125302014Genetic modifiers of EGFR dependence in non-small cell lung cancer.36
235956352013Changes in aberrant DNA methylation after Helicobacter pylori eradication: a long-term follow-up study.28
235956352013Changes in aberrant DNA methylation after Helicobacter pylori eradication: a long-term follow-up study.28
222525842012Prediction of the risk for gastric cancer using candidate methylation markers in the non-neoplastic gastric mucosae.19
222525842012Prediction of the risk for gastric cancer using candidate methylation markers in the non-neoplastic gastric mucosae.19
201861242010Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.85
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.28
201861242010Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.85
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.28
182465412008Mos 3' UTR regulatory differences underlie species-specific temporal patterns of Mos mRNA cytoplasmic polyadenylation and translational recruitment during oocyte maturation.11
185507952008Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.15
182465412008Mos 3' UTR regulatory differences underlie species-specific temporal patterns of Mos mRNA cytoplasmic polyadenylation and translational recruitment during oocyte maturation.11

Citation

Dessen P

MOS (MOS proto-oncogene, serine/threonine kinase)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41414/mos-(mos-proto-oncogene-serine-threonine-kinase)