MXD4 (MAX dimerization protein 4)

2003-05-01  

Identity

HGNC
MXD4
LOCATION
4p16.3
LOCUSID
10608
ALIAS
MAD4,MST149,MSTP149,bHLHc12
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10608
HGNC: 13906
Ensembl: ENSG00000123933

Variants:

dbSNP: 10608
ClinVar: 10608
TCGA: ENSG00000123933
COSMIC: MXD4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123933ENST00000337190Q14582
ENSG00000123933ENST00000510822D6RGV1
ENSG00000123933ENST00000513380H0Y8Z5

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
360075502023MXD4/MAD4 Regulates Human Keratinocyte Precursor Fate.1
360075502023MXD4/MAD4 Regulates Human Keratinocyte Precursor Fate.1
363028552022Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.8
363028552022Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.8
337149832021NUTM1-rearranged colorectal sarcoma: a clinicopathologically and genetically distinctive malignant neoplasm with a poor prognosis.7
337149832021NUTM1-rearranged colorectal sarcoma: a clinicopathologically and genetically distinctive malignant neoplasm with a poor prognosis.7
228950692012Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells.6
228950692012Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells.6
161673422005c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts.6
161673422005c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts.6
154697262004Human liver specific transcriptional factor TCP10L binds to MAD4.2
154697262004Human liver specific transcriptional factor TCP10L binds to MAD4.2
124189612003Mad4 is regulated by a transcriptional repressor complex that contains Miz-1 and c-Myc.23
124189612003Mad4 is regulated by a transcriptional repressor complex that contains Miz-1 and c-Myc.23

Citation

Dessen P

MXD4 (MAX dimerization protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41465/css/deep-insight-explorer/gene-fusions-explorer/