NCAM2 (neural cell adhesion molecule 2)

2003-11-01  

Identity

HGNC
LOCATION
21q21.1
LOCUSID
ALIAS
NCAM21
FUSION GENES

Other Information

Locus ID:

NCBI: 4685
MIM: 602040
HGNC: 7657
Ensembl: ENSG00000154654

Variants:

dbSNP: 4685
ClinVar: 4685
TCGA: ENSG00000154654
COSMIC: NCAM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154654ENST00000284894H9KV31
ENSG00000154654ENST00000400546O15394

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
Prion diseasesKEGGko05020
Prion diseasesKEGGhsa05020

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
335482232021Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo.9
335482232021Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo.9
320431202020NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3.15
320431202020NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3.15
298958982018NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor.12
298958982018NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor.12
275966832016NCAM2 deletion in a boy with macrocephaly and autism: Cause, association or predisposition?10
275966832016NCAM2 deletion in a boy with macrocephaly and autism: Cause, association or predisposition?10
266112612015Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.44
266112612015Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.44
212146742011Neural cell adhesion molecule 2 as a target molecule for prostate and breast cancer gene therapy.9
213002892011Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule.18
212146742011Neural cell adhesion molecule 2 as a target molecule for prostate and breast cancer gene therapy.9
213002892011Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule.18
200294092010Association of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters.2

Citation

Dessen P

NCAM2 (neural cell adhesion molecule 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41504/teaching-explorer/meetings/deep-insight-explorer/