NUDT11 (nudix hydrolase 11)

2003-05-01  

Identity

HGNC
LOCATION
Xp11.22
LOCUSID
ALIAS
APS1,ASP1,DIPP3b,DIPP3beta,hDIPP3beta

Other Information

Locus ID:

NCBI: 55190
MIM: 300528
HGNC: 18011
Ensembl: ENSG00000196368

Variants:

dbSNP: 55190
ClinVar: 55190
TCGA: ENSG00000196368
COSMIC: NUDT11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196368ENST00000375992Q96G61

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Inositol phosphate metabolismREACTOMER-HSA-1483249
Synthesis of pyrophosphates in the cytosolREACTOMER-HSA-1855167

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
227304612012Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.72
227304612012Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.72
210715402011Validation of genome-wide prostate cancer associations in men of African descent.59
210715402011Validation of genome-wide prostate cancer associations in men of African descent.59
199024742010Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans.44
199024742010Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans.44
121052282002An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.16
121215772002Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.20
121052282002An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.16
121215772002Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.20

Citation

Dessen P

NUDT11 (nudix hydrolase 11)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41591/js/lib/deep-insight-explorer/