SLC45A3 (solute carrier family 45 member 3)

2003-02-01  

Identity

HGNC
SLC45A3
LOCATION
1q32.1
LOCUSID
85414
ALIAS
IPCA-2,IPCA-6,IPCA-8,IPCA6,PCANAP2,PCANAP6,PCANAP8,PRST
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 85414
MIM: 605097
HGNC: 8642
Ensembl: ENSG00000158715

Variants:

dbSNP: 85414
ClinVar: 85414
TCGA: ENSG00000158715
COSMIC: SLC45A3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158715ENST00000367145Q96JT2

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Hexose transportREACTOMER-HSA-189200
Glucose transportREACTOMER-HSA-70153
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382188962024Prostein expression in human tumors: a tissue microarray study on 19,202 tumors from 152 different Tumor entities.0
382188962024Prostein expression in human tumors: a tissue microarray study on 19,202 tumors from 152 different Tumor entities.0
340998642021Mapping genetic variability in mature miRNAs and miRNA binding sites in prostate cancer.3
340998642021Mapping genetic variability in mature miRNAs and miRNA binding sites in prostate cancer.3
330450052020Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.65
330450052020Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.65
277001032017Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer.7
277001032017Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer.7
269388742016Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA.15
269388742016Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA.15
254344962015Genetic variants at 1q32.1, 10q11.2 and 19q13.41 are associated with prostate-specific antigen for prostate cancer screening in two Korean population-based cohort studies.12
254344962015Genetic variants at 1q32.1, 10q11.2 and 19q13.41 are associated with prostate-specific antigen for prostate cancer screening in two Korean population-based cohort studies.12
228217572013Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated with SLC45A3-ERG gene rearrangement and an unfavorable clinical course.19
232695362013Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population.12
228217572013Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated with SLC45A3-ERG gene rearrangement and an unfavorable clinical course.19

Citation

Dessen P

SLC45A3 (solute carrier family 45 member 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41657/css/humanGenome