RAB34 (RAB34, member RAS oncogene family)

2003-12-01  

Identity

HGNC
RAB34
LOCATION
17q11.2
LOCUSID
83871
ALIAS
NARR,RAB39,RAH

Other Information

Locus ID:

NCBI: 83871
MIM: 610917
HGNC: 16519
Ensembl: ENSG00000109113

Variants:

dbSNP: 83871
ClinVar: 83871
TCGA: ENSG00000109113
COSMIC: RAB34

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109113ENST00000301043Q9BZG1
ENSG00000109113ENST00000301043A0A024QZ68
ENSG00000109113ENST00000353676C9JBG0
ENSG00000109113ENST00000395243A0A1C7CYW6
ENSG00000109113ENST00000395245Q9BZG1
ENSG00000109113ENST00000395245A0A024QZ68
ENSG00000109113ENST00000412625C9JBG0
ENSG00000109113ENST00000415040Q9BZG1
ENSG00000109113ENST00000419712K7EIF2
ENSG00000109113ENST00000422279H7C0Y7
ENSG00000109113ENST00000430132C9JY26
ENSG00000109113ENST00000436730Q9BZG1
ENSG00000109113ENST00000436730A0A024QZ68
ENSG00000109113ENST00000450529Q9BZG1
ENSG00000109113ENST00000453384E7ES60
ENSG00000109113ENST00000580843K7EJW7
ENSG00000109113ENST00000582934V9GY61
ENSG00000109113ENST00000583538J3QLC6
ENSG00000109113ENST00000625712Q96PJ7
ENSG00000109113ENST00000636154P0DI83
ENSG00000109113ENST00000636513A0A1B0GWB1
ENSG00000109113ENST00000636534A0A1B0GVI6
ENSG00000109113ENST00000636772A0A1B0GTQ2

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381830572024Localization, traffic and function of Rab34 in adipocyte lipid and endocrine functions.0
381830572024Localization, traffic and function of Rab34 in adipocyte lipid and endocrine functions.0
373843952023Pathogenic RAB34 variants impair primary cilium assembly and cause a novel oral-facial-digital syndrome.2
373843952023Pathogenic RAB34 variants impair primary cilium assembly and cause a novel oral-facial-digital syndrome.2
352859602022Rab34 plays a critical role as a bidirectional regulator of osteoclastogenesis.0
352859602022Rab34 plays a critical role as a bidirectional regulator of osteoclastogenesis.0
339895272021Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway.21
339895272021Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway.21
326693612020A comprehensive analysis of Rab GTPases reveals a role for Rab34 in serum starvation-induced primary ciliogenesis.12
326693612020A comprehensive analysis of Rab GTPases reveals a role for Rab34 in serum starvation-induced primary ciliogenesis.12
296227942018Rab34 regulates adhesion, migration, and invasion of breast cancer cells.21
303017812018Rab34 small GTPase is required for Hedgehog signaling and an early step of ciliary vesicle formation in mouse.16
296227942018Rab34 regulates adhesion, migration, and invasion of breast cancer cells.21
303017812018Rab34 small GTPase is required for Hedgehog signaling and an early step of ciliary vesicle formation in mouse.16
281853472017Salmonella effector SopD2 interferes with Rab34 function.6

Citation

Dessen P

RAB34 (RAB34, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41982/js/lib/js/lib/haematological-explorer/