RHOJ (ras homolog family member J)

2004-04-01  

Identity

HGNC
RHOJ
LOCATION
14q23.2
LOCUSID
57381
ALIAS
ARHJ,RASL7B,TC10B,TCL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57381
MIM: 607653
HGNC: 688
Ensembl: ENSG00000126785

Variants:

dbSNP: 57381
ClinVar: 57381
TCGA: ENSG00000126785
COSMIC: RHOJ

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126785ENST00000316754Q9H4E5
ENSG00000126785ENST00000316754A0A024R692
ENSG00000126785ENST00000555125G3V476
ENSG00000126785ENST00000557447G3V4H1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382478652024Towards Understanding the Development of Breast Cancer: The Role of RhoJ in the Obesity Microenvironment.0
382478652024Towards Understanding the Development of Breast Cancer: The Role of RhoJ in the Obesity Microenvironment.0
377810362023RHOJ Induces Epithelial-to-Mesenchymal Transition by IL-6/STAT3 to Promote Invasion and Metastasis in Gastric Cancer.2
377810362023RHOJ Induces Epithelial-to-Mesenchymal Transition by IL-6/STAT3 to Promote Invasion and Metastasis in Gastric Cancer.2
341198292021Repression of RhoJ expression promotes TGF-β-mediated EMT in human non-small-cell lung cancer A549cells.5
341198292021Repression of RhoJ expression promotes TGF-β-mediated EMT in human non-small-cell lung cancer A549cells.5
316384122020A Protective Role for RHOJ in NonSmall Cell Lung Cancer Based on Integrated Bioinformatics Analysis.4
323025852020RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.17
323475712020RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells.13
328220012020Rhoj Is a Novel Target for Progression and Invasion of Glioblastoma by Impairing Cytoskeleton Dynamics.9
316384122020A Protective Role for RHOJ in NonSmall Cell Lung Cancer Based on Integrated Bioinformatics Analysis.4
323025852020RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.17
323475712020RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells.13
328220012020Rhoj Is a Novel Target for Progression and Invasion of Glioblastoma by Impairing Cytoskeleton Dynamics.9
287536062017The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas.14

Citation

Dessen P

RHOJ (ras homolog family member J)

Atlas Genet Cytogenet Oncol Haematol. 2004-04-01

Online version: http://atlasgeneticsoncology.org/gene/42112/gene-explorer/deep-insight-explorer/welcome