RHOJ (ras homolog family member J)

2004-04-01  

Identity

HGNC
LOCATION
14q23.2
LOCUSID
ALIAS
ARHJ,RASL7B,TC10B,TCL
FUSION GENES

Other Information

Locus ID:

NCBI: 57381
MIM: 607653
HGNC: 688
Ensembl: ENSG00000126785

Variants:

dbSNP: 57381
ClinVar: 57381
TCGA: ENSG00000126785
COSMIC: RHOJ

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126785ENST00000316754Q9H4E5
ENSG00000126785ENST00000316754A0A024R692
ENSG00000126785ENST00000555125G3V476
ENSG00000126785ENST00000557447G3V4H1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382478652024Towards Understanding the Development of Breast Cancer: The Role of RhoJ in the Obesity Microenvironment.0
382478652024Towards Understanding the Development of Breast Cancer: The Role of RhoJ in the Obesity Microenvironment.0
377810362023RHOJ Induces Epithelial-to-Mesenchymal Transition by IL-6/STAT3 to Promote Invasion and Metastasis in Gastric Cancer.2
377810362023RHOJ Induces Epithelial-to-Mesenchymal Transition by IL-6/STAT3 to Promote Invasion and Metastasis in Gastric Cancer.2
341198292021Repression of RhoJ expression promotes TGF-β-mediated EMT in human non-small-cell lung cancer A549cells.5
341198292021Repression of RhoJ expression promotes TGF-β-mediated EMT in human non-small-cell lung cancer A549cells.5
316384122020A Protective Role for RHOJ in NonSmall Cell Lung Cancer Based on Integrated Bioinformatics Analysis.4
323025852020RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.17
323475712020RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells.13
328220012020Rhoj Is a Novel Target for Progression and Invasion of Glioblastoma by Impairing Cytoskeleton Dynamics.9
316384122020A Protective Role for RHOJ in NonSmall Cell Lung Cancer Based on Integrated Bioinformatics Analysis.4
323025852020RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.17
323475712020RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells.13
328220012020Rhoj Is a Novel Target for Progression and Invasion of Glioblastoma by Impairing Cytoskeleton Dynamics.9
287536062017The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas.14

Citation

Dessen P

RHOJ (ras homolog family member J)

Atlas Genet Cytogenet Oncol Haematol. 2004-04-01

Online version: http://atlasgeneticsoncology.org/gene/42112/js/lib/gene-explorer/gene-fusions/?id=42112