RPS3 (ribosomal protein S3)

2003-06-01  

Identity

HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
S3
FUSION GENES

Other Information

Locus ID:

NCBI: 6188
MIM: 600454
HGNC: 10420
Ensembl: ENSG00000149273

Variants:

dbSNP: 6188
ClinVar: 6188
TCGA: ENSG00000149273
COSMIC: RPS3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149273ENST00000278572P23396
ENSG00000149273ENST00000422465E9PSF4
ENSG00000149273ENST00000524851P23396
ENSG00000149273ENST00000525690H0YES8
ENSG00000149273ENST00000525933H0YEU2
ENSG00000149273ENST00000526248H0YCJ7
ENSG00000149273ENST00000526608E9PL09
ENSG00000149273ENST00000527273E9PK82
ENSG00000149273ENST00000527446P23396
ENSG00000149273ENST00000528439E9PQ96
ENSG00000149273ENST00000528847E9PJN9
ENSG00000149273ENST00000530164F2Z2S8
ENSG00000149273ENST00000530170H0YF32
ENSG00000149273ENST00000530721E9PQX2
ENSG00000149273ENST00000531188P23396
ENSG00000149273ENST00000532872E9PJH4
ENSG00000149273ENST00000534440E9PPU1

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Ribosome, eukaryotesKEGGhsa_M00177
Ribosome, eukaryotesKEGGM00177
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
Formation of the ternary complex, and subsequently, the 43S complexREACTOMER-HSA-72695
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SREACTOMER-HSA-72662
Translation initiation complex formationREACTOMER-HSA-72649
Ribosomal scanning and start codon recognitionREACTOMER-HSA-72702
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Eukaryotic Translation ElongationREACTOMER-HSA-156842
Peptide chain elongationREACTOMER-HSA-156902
Eukaryotic Translation TerminationREACTOMER-HSA-72764
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Influenza InfectionREACTOMER-HSA-168254
Influenza Life CycleREACTOMER-HSA-168255
Influenza Viral RNA Transcription and ReplicationREACTOMER-HSA-168273
Viral mRNA TranslationREACTOMER-HSA-192823
Gene ExpressionREACTOMER-HSA-74160
Nonsense-Mediated Decay (NMD)REACTOMER-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)REACTOMER-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)REACTOMER-HSA-975956
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Selenoamino acid metabolismREACTOMER-HSA-2408522
Selenocysteine synthesisREACTOMER-HSA-2408557
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363960972023AP lyase activity of the human ribosomal protein uS3: The DNA cleavage sequence specificity and the location of the enzyme active center.0
365673442023UBE2J1 inhibits colorectal cancer progression by promoting ubiquitination and degradation of RPS3.9
367249042023Phosphorylation of rpS3 by Lyn increases translation of Multi-Drug Resistance (MDR1) gene.1
370701892023Selective translational control of cellular and viral mRNAs by RPS3 mRNA binding.6
363960972023AP lyase activity of the human ribosomal protein uS3: The DNA cleavage sequence specificity and the location of the enzyme active center.0
365673442023UBE2J1 inhibits colorectal cancer progression by promoting ubiquitination and degradation of RPS3.9
367249042023Phosphorylation of rpS3 by Lyn increases translation of Multi-Drug Resistance (MDR1) gene.1
370701892023Selective translational control of cellular and viral mRNAs by RPS3 mRNA binding.6
356161352022Mesothelin‑specific T cell cytotoxicity against triple negative breast cancer is enhanced by 40s ribosomal protein subunit 3‑treated self‑differentiated dendritic cells.1
361967222022RPS3 predicts poor overall survival in HBV-related hepatocellular carcinoma patients: a data-mining with LASSO-regression algorithm.0
356161352022Mesothelin‑specific T cell cytotoxicity against triple negative breast cancer is enhanced by 40s ribosomal protein subunit 3‑treated self‑differentiated dendritic cells.1
361967222022RPS3 predicts poor overall survival in HBV-related hepatocellular carcinoma patients: a data-mining with LASSO-regression algorithm.0
340703322021Fucosylated Proteome Profiling Identifies a Fucosylated, Non-Ribosomal, Stress-Responsive Species of Ribosomal Protein S3.3
344126522021A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation.33
340703322021Fucosylated Proteome Profiling Identifies a Fucosylated, Non-Ribosomal, Stress-Responsive Species of Ribosomal Protein S3.3

Citation

Dessen P

RPS3 (ribosomal protein S3)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42164/meetings/humanGenome