RXRB (retinoid X receptor beta)

2003-08-01  

Identity

HGNC
RXRB
LOCATION
6p21.32
LOCUSID
6257
ALIAS
DAUDI6,H-2RIIBP,NR2B2,RCoR-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6257
MIM: 180246
HGNC: 10478
Ensembl: ENSG00000204231

Variants:

dbSNP: 6257
ClinVar: 6257
TCGA: ENSG00000204231
COSMIC: RXRB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204231ENST00000374680P28702
ENSG00000204231ENST00000374680Q5STP9
ENSG00000204231ENST00000374685P28702
ENSG00000204231ENST00000374685A0A0S2Z570
ENSG00000204231ENST00000483281E9PK75

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
Adipocytokine signaling pathwayKEGGko04920
Thyroid cancerKEGGko05216
Small cell lung cancerKEGGko05222
Non-small cell lung cancerKEGGko05223
PPAR signaling pathwayKEGGhsa03320
Adipocytokine signaling pathwayKEGGhsa04920
Pathways in cancerKEGGhsa05200
Thyroid cancerKEGGhsa05216
Small cell lung cancerKEGGhsa05222
Non-small cell lung cancerKEGGhsa05223
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202
Thyroid hormone signaling pathwayKEGGhsa04919
Signal TransductionREACTOMER-HSA-162582
Signaling by Retinoic AcidREACTOMER-HSA-5362517
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Nuclear Receptor transcription pathwayREACTOMER-HSA-383280
Th17 cell differentiationKEGGko04659
Th17 cell differentiationKEGGhsa04659

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
332460822021Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.3
332460822021Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.3
263555502015Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.8
263555502015Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.8
241832352013Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.3
241832352013Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.3
223228852012A fatty acid-binding protein 7/RXRβ pathway enhances survival and proliferation in triple-negative breast cancer.35
223228852012A fatty acid-binding protein 7/RXRβ pathway enhances survival and proliferation in triple-negative breast cancer.35
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.30
205876102010Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.3
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.30
205876102010Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.3
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
191701962009Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.11

Citation

Dessen P

RXRB (retinoid X receptor beta)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/42187/gene-fusions/favicon/gene-fusions-explorer/