SSR2 (signal sequence receptor subunit 2)

2003-06-01  

Identity

HGNC
SSR2
LOCATION
1q22
LOCUSID
6746
ALIAS
HSD25,TLAP,TRAP-BETA,TRAPB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6746
MIM: 600867
HGNC: 11324
Ensembl: ENSG00000163479

Variants:

dbSNP: 6746
ClinVar: 6746
TCGA: ENSG00000163479
COSMIC: SSR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163479ENST00000295702P43308
ENSG00000163479ENST00000466905E9PJ35
ENSG00000163479ENST00000473699E9PNP2
ENSG00000163479ENST00000474377E9PJ35
ENSG00000163479ENST00000480567P43308
ENSG00000163479ENST00000496742E9PQJ7
ENSG00000163479ENST00000526212E9PQ05
ENSG00000163479ENST00000529008E9PN13
ENSG00000163479ENST00000531790E9PLP2
ENSG00000163479ENST00000531917E9PQI4

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Translocon-associated protein (TRAP) complexKEGGhsa_M00402
Translocon-associated protein (TRAP) complexKEGGM00402
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Gene ExpressionREACTOMER-HSA-74160

References

Pubmed IDYearTitleCitations
331373102020Translocon-Associated Protein Complex (TRAP) is Crucial for Co-Translational Translocation of Pre-Proinsulin.14
331373102020Translocon-Associated Protein Complex (TRAP) is Crucial for Co-Translational Translocation of Pre-Proinsulin.14
271803332016Signal Sequence Receptor 2 is required for survival of human melanoma cells as part of an unfolded protein response to endoplasmic reticulum stress.8
271803332016Signal Sequence Receptor 2 is required for survival of human melanoma cells as part of an unfolded protein response to endoplasmic reticulum stress.8
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

SSR2 (signal sequence receptor subunit 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42398/meetings/js/lib/teaching-explorer/