TAF9 (TATA-box binding protein associated factor 9)

2003-05-01  

Identity

HGNC
TAF9
LOCATION
5q13.2
LOCUSID
6880
ALIAS
MGC:5067,STAF31/32,TAF2G,TAFII-31,TAFII-32,TAFII31,TAFII32,TAFIID32

Other Information

Locus ID:

NCBI: 6880
MIM: 600822
HGNC: 11542
Ensembl: ENSG00000273841

Variants:

dbSNP: 6880
ClinVar: 6880
TCGA: ENSG00000273841
COSMIC: TAF9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000273841ENST00000217893Q16594
ENSG00000273841ENST00000328663Q16594
ENSG00000273841ENST00000503245D6RIE8
ENSG00000273841ENST00000504109D6RGK3
ENSG00000273841ENST00000506736Q16594
ENSG00000273841ENST00000508954D6RHW1
ENSG00000273841ENST00000509462D6RIV9
ENSG00000273841ENST00000512152D6RIY1

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Basal transcription factorsKEGGko03022
Basal transcription factorsKEGGhsa03022
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Transcription of the HIV genomeREACTOMER-HSA-167172
HIV Transcription InitiationREACTOMER-HSA-167161
RNA Polymerase II HIV Promoter EscapeREACTOMER-HSA-167162
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Pre-transcription EventsREACTOMER-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningREACTOMER-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter ClearanceREACTOMER-HSA-76042
RNA Polymerase II Transcription InitiationREACTOMER-HSA-75953
RNA Polymerase II Promoter EscapeREACTOMER-HSA-73776
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Activity through PhosphorylationREACTOMER-HSA-6804756
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
325418942020Human cytomegalovirus pp65 peptide-induced autoantibodies cross-reacts with TAF9 protein and induces lupus-like autoimmunity in BALB/c mice.9
325418942020Human cytomegalovirus pp65 peptide-induced autoantibodies cross-reacts with TAF9 protein and induces lupus-like autoimmunity in BALB/c mice.9
292572972018Cancer‑testis antigen HCA587/MAGEC2 interacts with the general transcription coactivator TAF9 in cancer cells.2
292572972018Cancer‑testis antigen HCA587/MAGEC2 interacts with the general transcription coactivator TAF9 in cancer cells.2
262821812015p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.21
262821812015p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.21
226962182012TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein.15
226962182012TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein.15
192516492009Distinct modes of gene regulation by a cell-specific transcriptional activator.23
196430372009Multiple hTAF(II)31-binding motifs in the intrinsically unfolded transcriptional activation domain of VP16.9
192516492009Distinct modes of gene regulation by a cell-specific transcriptional activator.23
196430372009Multiple hTAF(II)31-binding motifs in the intrinsically unfolded transcriptional activation domain of VP16.9
179678942008STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.45
179678942008STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.45
156018432005Core promoter binding by histone-like TAF complexes.34

Citation

Dessen P

TAF9 (TATA-box binding protein associated factor 9)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42466/img/js/cancer-prone-explorer/