TAT (tyrosine aminotransferase)

2003-02-01  

Identity

HGNC
TAT
LOCATION
16q22.2
LOCUSID
6898
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6898
MIM: 613018
HGNC: 11573
Ensembl: ENSG00000198650

Variants:

dbSNP: 6898
ClinVar: 6898
TCGA: ENSG00000198650
COSMIC: TAT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198650ENST00000355962P17735
ENSG00000198650ENST00000355962A0A140VKB7

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Ubiquinone and other terpenoid-quinone biosynthesisKEGGko00130
Tyrosine metabolismKEGGko00350
Phenylalanine metabolismKEGGko00360
Phenylalanine, tyrosine and tryptophan biosynthesisKEGGko00400
Ubiquinone and other terpenoid-quinone biosynthesisKEGGhsa00130
Tyrosine metabolismKEGGhsa00350
Phenylalanine metabolismKEGGhsa00360
Phenylalanine, tyrosine and tryptophan biosynthesisKEGGhsa00400
Cysteine and methionine metabolismKEGGko00270
Cysteine and methionine metabolismKEGGhsa00270
Metabolic pathwaysKEGGhsa01100
Methionine salvage pathwayKEGGhsa_M00034
Methionine salvage pathwayKEGGM00034
Biosynthesis of amino acidsKEGGhsa01230
Biosynthesis of amino acidsKEGGko01230
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Phenylalanine and tyrosine catabolismREACTOMER-HSA-71182
Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolismREACTOMER-HSA-6788656

References

Pubmed IDYearTitleCitations
386974622024TRIM21-mediated ubiquitylation of TAT suppresses liver metastasis in gallbladder cancer.0
386974622024TRIM21-mediated ubiquitylation of TAT suppresses liver metastasis in gallbladder cancer.0
368938722023Most synonymous allelic variants in HIV tat are not silent.1
368938722023Most synonymous allelic variants in HIV tat are not silent.1
282559852017Tyrosinemia type II: Mutation update, 11 novel mutations and description of 5 independent subjects with a novel founder mutation.9
282559852017Tyrosinemia type II: Mutation update, 11 novel mutations and description of 5 independent subjects with a novel founder mutation.9
272859492016Tyrosinemia type II: Novel mutations in TAT in a boy with unusual presentation.2
272859492016Tyrosinemia type II: Novel mutations in TAT in a boy with unusual presentation.2
239542272013Novel and recurrent mutations in the TAT gene in Tunisian families affected with Richner-Hanhart syndrome.5
239542272013Novel and recurrent mutations in the TAT gene in Tunisian families affected with Richner-Hanhart syndrome.5
216363002011A large TAT deletion in a tyrosinaemia type II patient.1
216363002011A large TAT deletion in a tyrosinaemia type II patient.1
202096012010Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.27
202096012010Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.27
187211272009Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells.3

Citation

Dessen P

TAT (tyrosine aminotransferase)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42472/js/js/welcome