ZNF10 (zinc finger protein 10)

2003-11-01  

Identity

HGNC
ZNF10
LOCATION
12q24.33
LOCUSID
7556
ALIAS
KOX1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7556
MIM: 194538
HGNC: 12879
Ensembl: ENSG00000256223

Variants:

dbSNP: 7556
ClinVar: 7556
TCGA: ENSG00000256223
COSMIC: ZNF10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000256223ENST00000248211P21506
ENSG00000256223ENST00000402932F8WD46
ENSG00000256223ENST00000426665P21506
ENSG00000256223ENST00000536877F5GZ75
ENSG00000256223ENST00000538918F5H0R3
ENSG00000256223ENST00000540609F5H311

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
351629972022The KRAB Domain of ZNF10 Guides the Identification of Specific Amino Acids That Transform the Ancestral KRAB-A-Related Domain Present in Human PRDM9 into a Canonical Modern KRAB-A Domain.4
351629972022The KRAB Domain of ZNF10 Guides the Identification of Specific Amino Acids That Transform the Ancestral KRAB-A-Related Domain Present in Human PRDM9 into a Canonical Modern KRAB-A Domain.4
260967822015ZNF10 inhibits HIV-1 LTR activity through interaction with NF-κB and Sp1 binding motifs.24
260967822015ZNF10 inhibits HIV-1 LTR activity through interaction with NF-κB and Sp1 binding motifs.24
244983432014The B-subdomain of the Xenopus laevis XFIN KRAB-AB domain is responsible for its weaker transcriptional repressor activity compared to human ZNF10/Kox1.4
244983432014The B-subdomain of the Xenopus laevis XFIN KRAB-AB domain is responsible for its weaker transcriptional repressor activity compared to human ZNF10/Kox1.4

Citation

Dessen P

ZNF10 (zinc finger protein 10)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/42869/haematological-explorer/deep-insight-explorer/