TUSC1 (tumor suppressor candidate 1)

2004-11-01 Affiliation

Identity

HGNC

TUSC1

LOCATION

9p21.2

LOCUSID

286319

ALIAS

CCDC89B,TSG-9,TSG9

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 286319
MIM: 610529
HGNC: 31010
Ensembl: ENSG00000198680

Variants:

dbSNP: 286319
ClinVar: 286319
TCGA: ENSG00000198680
COSMIC: TUSC1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000198680	ENST00000358022	Q2TAM9

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
35434854	2022	Circular RNA circ_0065378 upregulates tumor suppressor candidate 1 by competitively binding with miR-4701-5p to alleviate colorectal cancer progression.	7
35434854	2022	Circular RNA circ_0065378 upregulates tumor suppressor candidate 1 by competitively binding with miR-4701-5p to alleviate colorectal cancer progression.	7
28975488	2018	Association of TUSC1 and DPF3 gene polymorphisms with male infertility.	9
28975488	2018	Association of TUSC1 and DPF3 gene polymorphisms with male infertility.	9
26897357	2017	Tumor Suppressor Candidate 1 Suppresses Cell Growth and Predicts Better Survival in Glioblastoma.	7
26897357	2017	Tumor Suppressor Candidate 1 Suppresses Cell Growth and Predicts Better Survival in Glioblastoma.	7
24366000	2014	Identification of intragenic methylation in the TUSC1 gene as a novel prognostic marker of hepatocellular carcinoma.	11
24700496	2014	Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer.	14
24366000	2014	Identification of intragenic methylation in the TUSC1 gene as a novel prognostic marker of hepatocellular carcinoma.	11
24700496	2014	Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer.	14
23776618	2013	TUSC1, a putative tumor suppressor gene, reduces tumor cell growth in vitro and tumor growth in vivo.	19
23776618	2013	TUSC1, a putative tumor suppressor gene, reduces tumor cell growth in vitro and tumor growth in vivo.	19
20574843	2010	Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.	21
20574843	2010	Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.	21
15208665	2004	Identifying novel homozygous deletions by microsatellite analysis and characterization of tumor suppressor candidate 1 gene, TUSC1, on chromosome 9p in human lung cancer.	13

Citation

Dessen P

TUSC1 (tumor suppressor candidate 1)

Atlas Genet Cytogenet Oncol Haematol. 2004-11-01

Online version: http://atlasgeneticsoncology.org/gene/42955/css/hgnc