CDKL2 (cyclin dependent kinase like 2)

2006-10-01  

Identity

HGNC
CDKL2
LOCATION
4q21.1
LOCUSID
8999
ALIAS
KKIAMRE,P56
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8999
MIM: 603442
HGNC: 1782
Ensembl: ENSG00000138769

Variants:

dbSNP: 8999
ClinVar: 8999
TCGA: ENSG00000138769
COSMIC: CDKL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138769ENST00000307465J3KNE8
ENSG00000138769ENST00000429927Q92772
ENSG00000138769ENST00000429927A0A140VJG1
ENSG00000138769ENST00000506234D6RBJ5

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
321731422020Decreased CDKL2 expression is correlated with the progression and poor prognosis of glioma.5
331104562020Identification of a Set of Genes Improving Survival Prediction in Kidney Renal Clear Cell Carcinoma through Integrative Reanalysis of Transcriptomic Data.5
331788182020CDKL2 Is Associated with HER2 Status and Overall Survival in Gastric Cancer: Comparative Analysis of CDKL2 Protein Expression and Gene Copy Number.1
321731422020Decreased CDKL2 expression is correlated with the progression and poor prognosis of glioma.5
331104562020Identification of a Set of Genes Improving Survival Prediction in Kidney Renal Clear Cell Carcinoma through Integrative Reanalysis of Transcriptomic Data.5
331788182020CDKL2 Is Associated with HER2 Status and Overall Survival in Gastric Cancer: Comparative Analysis of CDKL2 Protein Expression and Gene Copy Number.1
302928712019Clinical significance of aberrant cyclin-dependent kinase-like 2 methylation in hepatocellular carcinoma.11
309532922019HSV-2-encoded miRNA-H4 Regulates Cell Cycle Progression and Act-D-induced Apoptosis in HeLa Cells by Targeting CDKL2 and CDKN2A.13
302928712019Clinical significance of aberrant cyclin-dependent kinase-like 2 methylation in hepatocellular carcinoma.11
309532922019HSV-2-encoded miRNA-H4 Regulates Cell Cycle Progression and Act-D-induced Apoptosis in HeLa Cells by Targeting CDKL2 and CDKN2A.13
253332622014CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression.24
253332622014CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression.24
166315992006Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck).8
166315992006Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck).8

Citation

Dessen P

CDKL2 (cyclin dependent kinase like 2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43204/favicon/cancer-prone-explorer/meetings/