DIRAS2 (DIRAS family GTPase 2)

2006-10-01  

Identity

HGNC
DIRAS2
LOCATION
9q22.2
LOCUSID
54769
ALIAS
Di-Ras2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54769
MIM: 607863
HGNC: 19323
Ensembl: ENSG00000165023

Variants:

dbSNP: 54769
ClinVar: 54769
TCGA: ENSG00000165023
COSMIC: DIRAS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165023ENST00000375765Q96HU8
ENSG00000165023ENST00000636786A0A1B0GVC3
ENSG00000165023ENST00000637905A0A1B0GWA9

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
349909892022ADHD patients with DIRAS2 risk allele need more thalamic activation during emotional face-voice recognition.0
351735352022Diverse Ras-related GTPase DIRAS2, downregulated by PSMD2 in a proteasome-mediated way, inhibits colorectal cancer proliferation by blocking NF-κB signaling.3
349909892022ADHD patients with DIRAS2 risk allele need more thalamic activation during emotional face-voice recognition.0
351735352022Diverse Ras-related GTPase DIRAS2, downregulated by PSMD2 in a proteasome-mediated way, inhibits colorectal cancer proliferation by blocking NF-κB signaling.3
321613112020Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel-Lindau protein.5
321613112020Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel-Lindau protein.5
294880992018Expression of the ADHD candidate gene Diras2 in the brain.3
294880992018Expression of the ADHD candidate gene Diras2 in the brain.3
273643292016Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism.2
273643292016Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism.2
217505792011DIRAS2 is associated with adult ADHD, related traits, and co-morbid disorders.15
217505792011DIRAS2 is associated with adult ADHD, related traits, and co-morbid disorders.15
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

DIRAS2 (DIRAS family GTPase 2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43230/favicon/humanGenome