MAST4 (microtubule associated serine/threonine kinase family member 4)

2006-10-01  

Identity

HGNC
MAST4
LOCATION
5q12.3
LOCUSID
375449
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 375449
MIM: 618002
HGNC: 19037
Ensembl: ENSG00000069020

Variants:

dbSNP: 375449
ClinVar: 375449
TCGA: ENSG00000069020
COSMIC: MAST4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000069020ENST00000261569O15021
ENSG00000069020ENST00000403625O15021
ENSG00000069020ENST00000403666O15021
ENSG00000069020ENST00000405643O15021
ENSG00000069020ENST00000406039E7EX28
ENSG00000069020ENST00000406374O15021
ENSG00000069020ENST00000407621B5MC73
ENSG00000069020ENST00000411628H7C146
ENSG00000069020ENST00000432426C9JKM7
ENSG00000069020ENST00000432817H7C3S4
ENSG00000069020ENST00000434115H7C0U3
ENSG00000069020ENST00000436277C9J249
ENSG00000069020ENST00000443808H7C1I9
ENSG00000069020ENST00000447738F8WBH1
ENSG00000069020ENST00000450827H7C2A9
ENSG00000069020ENST00000452953H7C2V7
ENSG00000069020ENST00000490016D6RAK1

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386128662024Nuclear MAST4 Suppresses FOXO3 through Interaction with AKT3 and Induces Chemoresistance in Pancreatic Ductal Carcinoma.0
386128662024Nuclear MAST4 Suppresses FOXO3 through Interaction with AKT3 and Induces Chemoresistance in Pancreatic Ductal Carcinoma.0
350649342022Estrogen-Responsive Gene MAST4 Regulates Myeloma Bone Disease.5
350649342022Estrogen-Responsive Gene MAST4 Regulates Myeloma Bone Disease.5
332193272021Mast4 knockout shows the regulation of spermatogonial stem cell self-renewal via the FGF2/ERM pathway.9
332193272021Mast4 knockout shows the regulation of spermatogonial stem cell self-renewal via the FGF2/ERM pathway.9
299483762018Clinical and genetic study of Tunisian families with genetic generalized epilepsy: contribution of CACNA1H and MAST4 genes.5
299483762018Clinical and genetic study of Tunisian families with genetic generalized epilepsy: contribution of CACNA1H and MAST4 genes.5
223604202012Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.24
223604202012Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.24
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
170869812006[Identification of a novel human MAST4 gene, a new member of the microtubule associated serine-threonine kinase family].10
170869812006[Identification of a novel human MAST4 gene, a new member of the microtubule associated serine-threonine kinase family].10

Citation

Dessen P

MAST4 (microtubule associated serine/threonine kinase family member 4)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43355/favicon/case-report-explorer/haematological-explorer/