RND1 (Rho family GTPase 1)

2006-10-01  

Identity

HGNC
RND1
LOCATION
12q13.12
LOCUSID
27289
ALIAS
ARHS,RHO6,RHOS

Other Information

Locus ID:

NCBI: 27289
MIM: 609038
HGNC: 18314
Ensembl: ENSG00000172602

Variants:

dbSNP: 27289
ClinVar: 27289
TCGA: ENSG00000172602
COSMIC: RND1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172602ENST00000309739Q92730
ENSG00000172602ENST00000550607H0YHG7
ENSG00000172602ENST00000551243F8VXU4

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Axon guidanceKEGGhsa04360
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Semaphorin interactionsREACTOMER-HSA-373755
Sema4D in semaphorin signalingREACTOMER-HSA-400685
Sema4D mediated inhibition of cell attachment and migrationREACTOMER-HSA-416550
Sema4D induced cell migration and growth-cone collapseREACTOMER-HSA-416572
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesionREACTOMER-HSA-399955

References

Pubmed IDYearTitleCitations
351022022022Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration.8
353340702022MiR-4652-5p Targets RND1 to Regulate Cell Adhesion and Promote Lung Squamous Cell Carcinoma Progression.0
356547952022Essential role of Rnd1 in innate immunity during viral and bacterial infections.1
351022022022Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration.8
353340702022MiR-4652-5p Targets RND1 to Regulate Cell Adhesion and Promote Lung Squamous Cell Carcinoma Progression.0
356547952022Essential role of Rnd1 in innate immunity during viral and bacterial infections.1
313448372019The RND1 Small GTPase: Main Functions and Emerging Role in Oncogenesis.9
313448372019The RND1 Small GTPase: Main Functions and Emerging Role in Oncogenesis.9
297066272018The Rho GTPase Rnd1 inhibits epithelial-mesenchymal transition in hepatocellular carcinoma and is a favorable anti-metastasis target.12
297066272018The Rho GTPase Rnd1 inhibits epithelial-mesenchymal transition in hepatocellular carcinoma and is a favorable anti-metastasis target.12
277703422017Attenuated RND1 Expression Confers Malignant Phenotype and Predicts Poor Prognosis in Hepatocellular Carcinoma.9
290402702017Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins.7
277703422017Attenuated RND1 Expression Confers Malignant Phenotype and Predicts Poor Prognosis in Hepatocellular Carcinoma.9
290402702017Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins.7
262504592016RND1 is up-regulated in esophageal squamous cell carcinoma and promotes the growth and migration of cancer cells.3

Citation

Dessen P

RND1 (Rho family GTPase 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43473/teaching-explorer/css/lib/case-report-explorer/favicon/manifest.json