CIAPIN1 (cytokine induced apoptosis inhibitor 1)

2007-02-01  

Identity

HGNC
CIAPIN1
LOCATION
16q21
LOCUSID
57019
ALIAS
Anamorsin,CIAE2,DRE2,PRO0915
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57019
MIM: 608943
HGNC: 28050
Ensembl: ENSG00000005194

Variants:

dbSNP: 57019
ClinVar: 57019
TCGA: ENSG00000005194
COSMIC: CIAPIN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000005194ENST00000394391Q6FI81
ENSG00000005194ENST00000563341H3BQ23
ENSG00000005194ENST00000565786H3BTT4
ENSG00000005194ENST00000565961H3BPG7
ENSG00000005194ENST00000567518Q6FI81
ENSG00000005194ENST00000567751H3BTZ8
ENSG00000005194ENST00000568940H3BT65
ENSG00000005194ENST00000569370H3BT65
ENSG00000005194ENST00000569979H3BV90
ENSG00000005194ENST00000570000H3BUG4

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Cytosolic iron-sulfur cluster assemblyREACTOMER-HSA-2564830

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
306375892019MiRNA-195-5p Functions as a Tumor Suppressor and a Predictive of Poor Prognosis in Non-small Cell Lung Cancer by Directly Targeting CIAPIN1.30
310933112019CIAPIN1 Targeted NHE1 and ERK1/2 to Suppress NSCLC Cells' Metastasis and Predicted Good Prognosis in NSCLC Patients Receiving Pulmonectomy.9
306375892019MiRNA-195-5p Functions as a Tumor Suppressor and a Predictive of Poor Prognosis in Non-small Cell Lung Cancer by Directly Targeting CIAPIN1.30
310933112019CIAPIN1 Targeted NHE1 and ERK1/2 to Suppress NSCLC Cells' Metastasis and Predicted Good Prognosis in NSCLC Patients Receiving Pulmonectomy.9
286480562017Anamorsin/Ndor1 Complex Reduces [2Fe-2S]-MitoNEET via a Transient Protein-Protein Interaction.18
286480562017Anamorsin/Ndor1 Complex Reduces [2Fe-2S]-MitoNEET via a Transient Protein-Protein Interaction.18
276441542016Cytokine-induced apoptosis inhibitor-1 causes dedifferentiation of rabbit articular chondrocytes via the ERK-1/2 and p38 kinase pathways.4
276441542016Cytokine-induced apoptosis inhibitor-1 causes dedifferentiation of rabbit articular chondrocytes via the ERK-1/2 and p38 kinase pathways.4
257248982015CIAPIN1 targets Na⁺/H⁺ exchanger 1 to mediate MDA-MB-231 cells' metastasis through regulation of MMPs via ERK1/2 signaling pathway.10
258896872015CIAPIN1 and ABCA13 are markers of poor survival in metastatic ovarian serous carcinoma.23
259015062015Cytokine-induced apoptosis inhibitor 1 inhibits the growth and proliferation of multiple myeloma.2
257248982015CIAPIN1 targets Na⁺/H⁺ exchanger 1 to mediate MDA-MB-231 cells' metastasis through regulation of MMPs via ERK1/2 signaling pathway.10
258896872015CIAPIN1 and ABCA13 are markers of poor survival in metastatic ovarian serous carcinoma.23
259015062015Cytokine-induced apoptosis inhibitor 1 inhibits the growth and proliferation of multiple myeloma.2
241232822014Crystal structure of the N-terminal methyltransferase-like domain of anamorsin.5

Citation

Dessen P

CIAPIN1 (cytokine induced apoptosis inhibitor 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43585/case-report-explorer/meetings/teaching-explorer/