CLEC3B (C-type lectin domain family 3 member B)

2007-02-01  

Identity

HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
TN,TNA
FUSION GENES

Other Information

Locus ID:

NCBI: 7123
MIM: 187520
HGNC: 11891
Ensembl: ENSG00000163815

Variants:

dbSNP: 7123
ClinVar: 7123
TCGA: ENSG00000163815
COSMIC: CLEC3B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163815ENST00000296130P05452
ENSG00000163815ENST00000296130A0A024R2Q7
ENSG00000163815ENST00000428034E9PHK0

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373104632023Tetranectin as a potential novel prognostic biomarker in anthracycline-related cardiac dysfunction.0
373104632023Tetranectin as a potential novel prognostic biomarker in anthracycline-related cardiac dysfunction.0
355005202022Down-regulation of CLEC3B facilitates epithelial-mesenchymal transition, migration and invasion of lung adenocarcinoma cells.4
355005202022Down-regulation of CLEC3B facilitates epithelial-mesenchymal transition, migration and invasion of lung adenocarcinoma cells.4
315709382020CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.2
326968212020CLEC3B protects H9c2 cardiomyocytes from apoptosis caused by hypoxia via the PI3K/Akt pathway.1
315709382020CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.2
326968212020CLEC3B protects H9c2 cardiomyocytes from apoptosis caused by hypoxia via the PI3K/Akt pathway.1
308584592019The In Vitro Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1.0
314771302019Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals.44
308584592019The In Vitro Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1.0
314771302019Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals.44
300669412018CLEC3B is downregulated and inhibits proliferation in clear cell renal cell carcinoma.17
300669412018CLEC3B is downregulated and inhibits proliferation in clear cell renal cell carcinoma.17
271549062017Exome-wide Association Study Identifies CLEC3B Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations.10

Citation

Dessen P

CLEC3B (C-type lectin domain family 3 member B)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43721/js/lib/meetings/