CLEC3B (C-type lectin domain family 3 member B)

2007-02-01 Affiliation

Identity

HGNC

CLEC3B

LOCATION

3p21.31

LOCUSID

7123

ALIAS

TN,TNA

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 7123
MIM: 187520
HGNC: 11891
Ensembl: ENSG00000163815

Variants:

dbSNP: 7123
ClinVar: 7123
TCGA: ENSG00000163815
COSMIC: CLEC3B

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000163815	ENST00000296130	P05452
ENSG00000163815	ENST00000296130	A0A024R2Q7
ENSG00000163815	ENST00000428034	E9PHK0

Expression (GTEx)

100

150

200

250

300

350

400

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Hemostasis	REACTOME	R-HSA-109582
Platelet activation, signaling and aggregation	REACTOME	R-HSA-76002
Response to elevated platelet cytosolic Ca2+	REACTOME	R-HSA-76005
Platelet degranulation	REACTOME	R-HSA-114608

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
37310463	2023	Tetranectin as a potential novel prognostic biomarker in anthracycline-related cardiac dysfunction.	0
37310463	2023	Tetranectin as a potential novel prognostic biomarker in anthracycline-related cardiac dysfunction.	0
35500520	2022	Down-regulation of CLEC3B facilitates epithelial-mesenchymal transition, migration and invasion of lung adenocarcinoma cells.	4
35500520	2022	Down-regulation of CLEC3B facilitates epithelial-mesenchymal transition, migration and invasion of lung adenocarcinoma cells.	4
31570938	2020	CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.	2
32696821	2020	CLEC3B protects H9c2 cardiomyocytes from apoptosis caused by hypoxia via the PI3K/Akt pathway.	1
31570938	2020	CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.	2
32696821	2020	CLEC3B protects H9c2 cardiomyocytes from apoptosis caused by hypoxia via the PI3K/Akt pathway.	1
30858459	2019	The In Vitro Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1.	0
31477130	2019	Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals.	44
30858459	2019	The In Vitro Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1.	0
31477130	2019	Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals.	44
30066941	2018	CLEC3B is downregulated and inhibits proliferation in clear cell renal cell carcinoma.	17
30066941	2018	CLEC3B is downregulated and inhibits proliferation in clear cell renal cell carcinoma.	17
27154906	2017	Exome-wide Association Study Identifies CLEC3B Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations.	10

Citation

Dessen P

CLEC3B (C-type lectin domain family 3 member B)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43721/meetings/welcome