ASF1B (anti-silencing function 1B histone chaperone)

2007-02-01  

Identity

HGNC
ASF1B
LOCATION
19p13.12
LOCUSID
55723
ALIAS
CIA-II
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55723
MIM: 609190
HGNC: 20996
Ensembl: ENSG00000105011

Variants:

dbSNP: 55723
ClinVar: 55723
TCGA: ENSG00000105011
COSMIC: ASF1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105011ENST00000263382Q9NVP2
ENSG00000105011ENST00000263382A0A024R7G4
ENSG00000105011ENST00000474890K7ELW9
ENSG00000105011ENST00000589468K7EM93
ENSG00000105011ENST00000590835K7EIL9
ENSG00000105011ENST00000592798K7ES22

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
testis
epididymis
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
374525102024CIA-II is associated with lower-grade glioma survival and cell proliferation.1
374525102024CIA-II is associated with lower-grade glioma survival and cell proliferation.1
359934692023ASF1B, as an Independent Prognostic Biomarker, Correlates with Immune Infiltrates in Hepatocellular Carcinoma.0
361149462023miR-24-3p Regulates Epithelial-Mesenchymal Transition and the Malignant Phenotype of Pancreatic Adenocarcinoma by Regulating ASF1B Expression.1
361782072023The circCDK17/miR-122-5p/ASF1B axis regulates the progression of cervical cancer.2
364163102023Anti‑silencing function 1B promotes the progression of pancreatic cancer by activating c‑Myc.2
369470602023The interaction between ASF1B and TLK1 promotes the malignant progression of low-grade glioma.2
359934692023ASF1B, as an Independent Prognostic Biomarker, Correlates with Immune Infiltrates in Hepatocellular Carcinoma.0
361149462023miR-24-3p Regulates Epithelial-Mesenchymal Transition and the Malignant Phenotype of Pancreatic Adenocarcinoma by Regulating ASF1B Expression.1
361782072023The circCDK17/miR-122-5p/ASF1B axis regulates the progression of cervical cancer.2
364163102023Anti‑silencing function 1B promotes the progression of pancreatic cancer by activating c‑Myc.2
369470602023The interaction between ASF1B and TLK1 promotes the malignant progression of low-grade glioma.2
351034782022ASF1B enhances migration and invasion of lung cancers cell via regulating the P53-mediated epithelial-mesenchymal transformation (EMT) signaling pathway.9
351360692022Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.9
351776092022RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity.6

Citation

Dessen P

ASF1B (anti-silencing function 1B histone chaperone)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43879/gene-explorer/case-report-explorer/