MT1F (metallothionein 1F)

2007-02-01  

Identity

HGNC
MT1F
LOCATION
16q13
LOCUSID
4494
ALIAS
MT1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4494
MIM: 156352
HGNC: 7398
Ensembl: ENSG00000198417

Variants:

dbSNP: 4494
ClinVar: 4494
TCGA: ENSG00000198417
COSMIC: MT1F

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198417ENST00000334350P04733
ENSG00000198417ENST00000568475H3BRY8

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
MetabolismREACTOMER-HSA-1430728
Response to metal ionsREACTOMER-HSA-5660526
Metallothioneins bind metalsREACTOMER-HSA-5661231

References

Pubmed IDYearTitleCitations
244404672014Significance of the rapid increase in GSH levels in the protective response to cadmium exposure through phosphorylated Nrf2 signaling in Jurkat T-cells.6
244404672014Significance of the rapid increase in GSH levels in the protective response to cadmium exposure through phosphorylated Nrf2 signaling in Jurkat T-cells.6
230640512013Metallothionein 1F and 2A overexpression predicts poor outcome of non-small cell lung cancer patients.26
233328812013Immunohistochemical expression of metallothionein in pleomorphic adenoma of minor salivary glands: a role in the control of apoptosis?0
235369592013Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2.34
230640512013Metallothionein 1F and 2A overexpression predicts poor outcome of non-small cell lung cancer patients.26
233328812013Immunohistochemical expression of metallothionein in pleomorphic adenoma of minor salivary glands: a role in the control of apoptosis?0
235369592013Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2.34
218201542012Metallothionein expression in colorectal cancer: relevance of different isoforms for tumor progression and patient survival.28
224260382012Downregulation of metallothionein 1F, a putative oncosuppressor, by loss of heterozygosity in colon cancer tissue.25
218201542012Metallothionein expression in colorectal cancer: relevance of different isoforms for tumor progression and patient survival.28
224260382012Downregulation of metallothionein 1F, a putative oncosuppressor, by loss of heterozygosity in colon cancer tissue.25
211280012011Metallothionein-1 genotypes in the risk of oral squamous cell carcinoma.14
214092062011The "magic numbers" of metallothionein.54
211280012011Metallothionein-1 genotypes in the risk of oral squamous cell carcinoma.14

Citation

Dessen P

MT1F (metallothionein 1F)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45639/cancer-prone-explorer/teaching-explorer/