IFI27 (interferon alpha inducible protein 27)

2007-02-01  

Identity

HGNC
LOCATION
14q32.12
LOCUSID
ALIAS
FAM14D,ISG12,ISG12A,P27
FUSION GENES

Other Information

Locus ID:

NCBI: 3429
MIM: 600009
HGNC: 5397
Ensembl: ENSG00000165949

Variants:

dbSNP: 3429
ClinVar: 3429
TCGA: ENSG00000165949
COSMIC: IFI27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165949ENST00000555819G3V4U3
ENSG00000165949ENST00000612813P40305
ENSG00000165949ENST00000614204A0A087WV79
ENSG00000165949ENST00000614288A0A087X035
ENSG00000165949ENST00000616764P40305
ENSG00000165949ENST00000618200A0A087WUJ8
ENSG00000165949ENST00000618863P40305
ENSG00000165949ENST00000620066A0A087WZR1
ENSG00000165949ENST00000620396A0A087X174
ENSG00000165949ENST00000621160P40305

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon alpha/beta signalingREACTOMER-HSA-909733

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367485182023Knockdown of NEAT1 restricts dengue virus replication by augmenting interferon alpha-inducible protein 27 via the RIG-I pathway.5
369711412023Integrative bulk and single-cell transcriptome profiling analysis reveals IFI27 as a novel interferon-stimulated gene in dengue.1
371026432023Behçet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions.1
367485182023Knockdown of NEAT1 restricts dengue virus replication by augmenting interferon alpha-inducible protein 27 via the RIG-I pathway.5
369711412023Integrative bulk and single-cell transcriptome profiling analysis reveals IFI27 as a novel interferon-stimulated gene in dengue.1
371026432023Behçet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions.1
353463242022PABPC1-induced stabilization of IFI27 mRNA promotes angiogenesis and malignant progression in esophageal squamous cell carcinoma through exosomal miRNA-21-5p.18
358207052022ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF.19
359743842022MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection.4
366856002022IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study.17
353463242022PABPC1-induced stabilization of IFI27 mRNA promotes angiogenesis and malignant progression in esophageal squamous cell carcinoma through exosomal miRNA-21-5p.18
358207052022ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF.19
359743842022MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection.4
366856002022IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study.17
333880932021IFI27 may predict and evaluate the severity of respiratory syncytial virus infection in preterm infants.10

Citation

Dessen P

IFI27 (interferon alpha inducible protein 27)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46294/favicon/js/hgnc