USF2 (upstream transcription factor 2, c-fos interacting)

2007-02-01  

Identity

HGNC
USF2
LOCATION
19q13.12
LOCUSID
7392
ALIAS
FIP,bHLHb12
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7392
MIM: 600390
HGNC: 12594
Ensembl: ENSG00000105698

Variants:

dbSNP: 7392
ClinVar: 7392
TCGA: ENSG00000105698
COSMIC: USF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105698ENST00000222305Q15853
ENSG00000105698ENST00000343550Q15853
ENSG00000105698ENST00000379134Q15853
ENSG00000105698ENST00000594064B4DLJ1
ENSG00000105698ENST00000595068Q15853
ENSG00000105698ENST00000596380M0R1C6
ENSG00000105698ENST00000597671M0QZ39
ENSG00000105698ENST00000598058M0QY46
ENSG00000105698ENST00000599471M0QXT0
ENSG00000105698ENST00000599625M0QYU7
ENSG00000105698ENST00000602164V9GYR5

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
369051062023WDR3 promotes stem cell-like properties in prostate cancer by inhibiting USF2-mediated transcription of RASSF1A.1
377127432023Long non-coding RNA X-Inactive Specific Transcript (XIST) interacting with USF2 promotes osteogenic differentiation of periodontal ligament stem cells through regulation of WDR72 transcription.1
369051062023WDR3 promotes stem cell-like properties in prostate cancer by inhibiting USF2-mediated transcription of RASSF1A.1
377127432023Long non-coding RNA X-Inactive Specific Transcript (XIST) interacting with USF2 promotes osteogenic differentiation of periodontal ligament stem cells through regulation of WDR72 transcription.1
347569232022USF2 knockdown downregulates THBS1 to inhibit the TGF-β signaling pathway and reduce pyroptosis in sepsis-induced acute kidney injury.29
362105782022Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2.6
363196312022USF2-mediated upregulation of TXNRD1 contributes to hepatocellular carcinoma progression by activating Akt/mTOR signaling.3
347569232022USF2 knockdown downregulates THBS1 to inhibit the TGF-β signaling pathway and reduce pyroptosis in sepsis-induced acute kidney injury.29
362105782022Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2.6
363196312022USF2-mediated upregulation of TXNRD1 contributes to hepatocellular carcinoma progression by activating Akt/mTOR signaling.3
343505222021USF2 reduces BMP3 expression via transcriptional activation of miR-34a, thus promoting osteogenic differentiation of BMSCs.2
343505222021USF2 reduces BMP3 expression via transcriptional activation of miR-34a, thus promoting osteogenic differentiation of BMSCs.2
314488312020USF2 enhances the osteogenic differentiation of PDLCs by promoting ATF4 transcriptional activities.5
321092892020Irrelevance of USF2 rs916145 polymorphism with the risk of biliary atresia susceptibility in Southern Chinese children.3
330010252020Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen.19

Citation

Dessen P

USF2 (upstream transcription factor 2, c-fos interacting)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46357/img/favicon/deep-insight-explorer/