NAV3 (neuron navigator 3)

2007-04-01  

Identity

HGNC
NAV3
LOCATION
12q21.2
LOCUSID
89795
ALIAS
POMFIL1,STEERIN3,unc53H3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 89795
MIM: 611629
HGNC: 15998
Ensembl: ENSG00000067798

Variants:

dbSNP: 89795
ClinVar: 89795
TCGA: ENSG00000067798
COSMIC: NAV3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000067798ENST00000397909Q8IVL0
ENSG00000067798ENST00000536525Q8IVL0
ENSG00000067798ENST00000549464F8VZV4
ENSG00000067798ENST00000550042A0A1B0GTC4
ENSG00000067798ENST00000550503H0YHX7
ENSG00000067798ENST00000550788H0YI14
ENSG00000067798ENST00000552895H0YHA8
ENSG00000067798ENST00000644176A0A2R8YFX5

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368838772023Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours.0
368838772023Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours.0
256785582015Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.18
262104482015MiR-21 promoted proliferation and migration in hepatocellular carcinoma through negative regulation of Navigator-3.10
256785582015Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.18
262104482015MiR-21 promoted proliferation and migration in hepatocellular carcinoma through negative regulation of Navigator-3.10
230971412013Neuron navigator 3 alterations in nervous system tumors associate with tumor malignancy grade and prognosis.14
230971412013Neuron navigator 3 alterations in nervous system tumors associate with tumor malignancy grade and prognosis.14
221736702012Potential role of a navigator gene NAV3 in colorectal cancer.18
221736702012Potential role of a navigator gene NAV3 in colorectal cancer.18
219958142011NAV3 copy number changes and target genes in basal and squamous cell cancers.7
219958142011NAV3 copy number changes and target genes in basal and squamous cell cancers.7
196260312010Cutaneous-type adult T-cell leukemia/lymphoma does not primarily show deletion of NAV3 gene.0
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15

Citation

Dessen P

NAV3 (neuron navigator 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46629/gene-fusions-explorer/case-report-explorer/