PPP1R1C (protein phosphatase 1 regulatory inhibitor subunit 1C)

2007-04-01  

Identity

HGNC
PPP1R1C
LOCATION
2q31.3
LOCUSID
151242
ALIAS
IPP5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 151242
MIM: 613240
HGNC: 14940
Ensembl: ENSG00000150722

Variants:

dbSNP: 151242
ClinVar: 151242
TCGA: ENSG00000150722
COSMIC: PPP1R1C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000150722ENST00000280295Q8WVI7
ENSG00000150722ENST00000409137Q8WVI7
ENSG00000150722ENST00000409702Q8WVI7

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
2493560420148-60hIPP5(m)-induced G2/M cell cycle arrest involves activation of ATM/p53/p21(cip1/waf1) pathways and delayed cyclin B1 nuclear translocation.3
253390262014Sensitization of cervical carcinoma cells to paclitaxel by an IPP5 active mutant.1
2493560420148-60hIPP5(m)-induced G2/M cell cycle arrest involves activation of ATM/p53/p21(cip1/waf1) pathways and delayed cyclin B1 nuclear translocation.3
253390262014Sensitization of cervical carcinoma cells to paclitaxel by an IPP5 active mutant.1
229393972012IPP5, a novel inhibitor of protein phosphatase 1, suppresses tumor growth and progression of cervical carcinoma cells by inducing G2/M arrest.1
229393972012IPP5, a novel inhibitor of protein phosphatase 1, suppresses tumor growth and progression of cervical carcinoma cells by inducing G2/M arrest.1
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
204680712010Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.22
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
204680712010Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.22
198742722009Effect of IPP5, a novel inhibitor of PP1, on apoptosis and the underlying mechanisms involved.5
198742722009Effect of IPP5, a novel inhibitor of PP1, on apoptosis and the underlying mechanisms involved.5

Citation

Dessen P

PPP1R1C (protein phosphatase 1 regulatory inhibitor subunit 1C)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47023/meetings/favicon/welcome