E2F7 (E2F transcription factor 7)

2007-04-01  

Identity

HGNC
E2F7
LOCATION
12q21.2
LOCUSID
144455
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 144455
MIM: 612046
HGNC: 23820
Ensembl: ENSG00000165891

Variants:

dbSNP: 144455
ClinVar: 144455
TCGA: ENSG00000165891
COSMIC: E2F7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165891ENST00000322886Q96AV8
ENSG00000165891ENST00000416496Q96AV8
ENSG00000165891ENST00000547316F8VXV5
ENSG00000165891ENST00000550669F8VSE7
ENSG00000165891ENST00000551058H0YIF4
ENSG00000165891ENST00000552907H0YHW2

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
TP53 Regulates Transcription of Cell Cycle GenesREACTOMER-HSA-6791312
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle ArrestREACTOMER-HSA-6804116

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA443560Breast NeoplasmsDiseaseClinicalAnnotationassociatedPD
PA451581tamoxifenChemicalClinicalAnnotationassociatedPD23508821

References

Pubmed IDYearTitleCitations
380733302024Transcription Factor E2F7 Hampers the Killing Effect of NK Cells against Colorectal Cancer Cells via Activating RAD18 Transcription.0
382415542024E2F7 serves as a potential prognostic biomarker for lung adenocarcinoma.0
384543442024p53/E2F7 axis promotes temozolomide chemoresistance in glioblastoma multiforme.2
380733302024Transcription Factor E2F7 Hampers the Killing Effect of NK Cells against Colorectal Cancer Cells via Activating RAD18 Transcription.0
382415542024E2F7 serves as a potential prognostic biomarker for lung adenocarcinoma.0
384543442024p53/E2F7 axis promotes temozolomide chemoresistance in glioblastoma multiforme.2
365252352023lncRNA ENST00000585827 Contributes to the Progression of Endometrial Carcinoma via Regulating miR-424/E2F6/E2F7 Axis.1
366275452023Circular RNA hsa_circ_0000519 contributes to angiogenesis and tumor progression in hepatocellular carcinoma through the miR-1296/E2F7 axis.4
367650372023Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7.1
370287652023VIRMA promotes nasopharyngeal carcinoma, tumorigenesis, and metastasis by upregulation of E2F7 in an m6A-dependent manner.3
372778642023Circ_0010235 confers cisplatin resistance in lung cancer by upregulating E2F7 through absorbing miR-379-5p.3
373588382023E2F7 drives autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not in human carcinomas.1
376157452023CISD2 transcriptional activated by transcription factor E2F7 promotes the malignant progression of cervical cancer.0
365252352023lncRNA ENST00000585827 Contributes to the Progression of Endometrial Carcinoma via Regulating miR-424/E2F6/E2F7 Axis.1
366275452023Circular RNA hsa_circ_0000519 contributes to angiogenesis and tumor progression in hepatocellular carcinoma through the miR-1296/E2F7 axis.4

Citation

Dessen P

E2F7 (E2F transcription factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47032/css/lib/tumors-explorer/cancer-prone-explorer/