ACYP2 (acylphosphatase 2)

2007-04-01  

Identity

HGNC
LOCATION
2p16.2
LOCUSID
ALIAS
ACYM,ACYP
FUSION GENES

Other Information

Locus ID:

NCBI: 98
MIM: 102595
HGNC: 180
Ensembl: ENSG00000170634

Variants:

dbSNP: 98
ClinVar: 98
TCGA: ENSG00000170634
COSMIC: ACYP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170634ENST00000303536F8WA34
ENSG00000170634ENST00000394666P14621
ENSG00000170634ENST00000394666A0A140VJD7
ENSG00000170634ENST00000406041E9PF46
ENSG00000170634ENST00000422521U3KQ94
ENSG00000170634ENST00000494922U3KPX1
ENSG00000170634ENST00000606082U3KQ09
ENSG00000170634ENST00000606865U3KPX8
ENSG00000170634ENST00000607452U3KQL2

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Pyruvate metabolismKEGGko00620
Pyruvate metabolismKEGGhsa00620

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA162263534OtotoxicityDiseaseClinicalAnnotationassociatedPD26928270, 31666714
PA443557Brain NeoplasmsDiseaseClinicalAnnotationassociatedPD26928270, 31666714
PA443840DeafnessDiseaseClinicalAnnotationassociatedPD26928270, 31666714
PA449014cisplatinChemicalClinicalAnnotationassociatedPD26928270, 31666714

References

Pubmed IDYearTitleCitations
386152712024Study of the effect of ACYP2 single nucleotide polymorphisms rs843711 and rs843706 in Egyptian patients with hepatocellular carcinoma.0
386152712024Study of the effect of ACYP2 single nucleotide polymorphisms rs843711 and rs843706 in Egyptian patients with hepatocellular carcinoma.0
329371842021The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM.4
339212542021Telomere Length and Male Fertility.12
329371842021The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM.4
339212542021Telomere Length and Male Fertility.12
325177172020ACYP2 contributes to malignant progression of glioma through promoting Ca(2+) efflux and subsequently activating c-Myc and STAT3 signals.4
325177172020ACYP2 contributes to malignant progression of glioma through promoting Ca(2+) efflux and subsequently activating c-Myc and STAT3 signals.4
303052942019Genetic and Modifiable Risk Factors Contributing to Cisplatin-induced Toxicities.31
310700192019The influence of ACYP2 polymorphisms on gastrointestinal cancer susceptibility in the Chinese Han population.2
311243132019Associations between polymorphisms of the ACYP2 gene and Liver cancer risk: A case-control study and meta-analysis.3
311407422019Assessment of the association between ACYP2 and laryngeal squamous cell carcinoma risk in Chinese males.1
312916402019Association between the ACYP2 Polymorphisms and IgAN Risk in the Chinese Han Population.0
314871242019Association between ACYP2 polymorphisms and the risk of renal cell cancer.2
303052942019Genetic and Modifiable Risk Factors Contributing to Cisplatin-induced Toxicities.31

Citation

Dessen P

ACYP2 (acylphosphatase 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47264/teaching-explorer/favicon/manifest.json