EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit)

2007-04-01  

Identity

HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
KMT6B
FUSION GENES

Other Information

Locus ID:

NCBI: 2145
MIM: 601674
HGNC: 3526
Ensembl: ENSG00000108799

Variants:

dbSNP: 2145
ClinVar: 2145
TCGA: ENSG00000108799
COSMIC: EZH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108799ENST00000415827A0A0A0MSY9
ENSG00000108799ENST00000428826Q92800
ENSG00000108799ENST00000585893Q92800
ENSG00000108799ENST00000586089K7EM79
ENSG00000108799ENST00000586382K7EIH5
ENSG00000108799ENST00000586867K7EJU6
ENSG00000108799ENST00000586935K7EK26
ENSG00000108799ENST00000588239K7ESB9
ENSG00000108799ENST00000588897K7ENP2
ENSG00000108799ENST00000590078Q92800
ENSG00000108799ENST00000592492K7EK66
ENSG00000108799ENST00000592743Q92800
ENSG00000108799ENST00000593214K7EPC0

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Lysine degradationKEGGko00310
Lysine degradationKEGGhsa00310

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383096752024The competitive mechanism of EZH1 and EZH2 in promoting oral squamous cell carcinoma.0
385544272024Clinical Significance of Upregulation of EZH1 Expression in Hepatocellular Carcinoma Tissues.0
383096752024The competitive mechanism of EZH1 and EZH2 in promoting oral squamous cell carcinoma.0
385544272024Clinical Significance of Upregulation of EZH1 Expression in Hepatocellular Carcinoma Tissues.0
374337832023Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders.5
374337832023Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders.5
348564182022TRIM21 improves apatinib treatment in gastric cancer through suppressing EZH1 stability.9
358468802022Downregulation of the enhancer of zeste homolog 1 transcriptional factor predicts poor prognosis of triple-negative breast cancer patients.1
360527162022Polycomb EZH1 regulates cell cycle/5-fluorouracil sensitivity of neuroblastoma cells in concert with MYCN.2
364762712022The role of EZH1 and EZH2 in development and cancer.7
348564182022TRIM21 improves apatinib treatment in gastric cancer through suppressing EZH1 stability.9
358468802022Downregulation of the enhancer of zeste homolog 1 transcriptional factor predicts poor prognosis of triple-negative breast cancer patients.1
360527162022Polycomb EZH1 regulates cell cycle/5-fluorouracil sensitivity of neuroblastoma cells in concert with MYCN.2
364762712022The role of EZH1 and EZH2 in development and cancer.7
335147052021Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.30

Citation

Dessen P

EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47297/gene-fusions-explorer/js/lib/favicon/manifest.json