COPS7B (COP9 signalosome subunit 7B)

2007-04-01  

Identity

HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
CSN7B,SGN7b
FUSION GENES

Other Information

Locus ID:

NCBI: 64708
MIM: 616010
HGNC: 16760
Ensembl: ENSG00000144524

Variants:

dbSNP: 64708
ClinVar: 64708
TCGA: ENSG00000144524
COSMIC: COPS7B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144524ENST00000350033Q9H9Q2
ENSG00000144524ENST00000350033A0A024R471
ENSG00000144524ENST00000357490J3KQV6
ENSG00000144524ENST00000373608Q9H9Q2
ENSG00000144524ENST00000409091Q9H9Q2
ENSG00000144524ENST00000409091A0A024R478
ENSG00000144524ENST00000409295J3KQ34
ENSG00000144524ENST00000410017J3KQ41
ENSG00000144524ENST00000410024Q9H9Q2
ENSG00000144524ENST00000410024A0A024R471
ENSG00000144524ENST00000412591J3QT95
ENSG00000144524ENST00000412922J3QT43
ENSG00000144524ENST00000413197J3QT67
ENSG00000144524ENST00000432387J3QT50
ENSG00000144524ENST00000436564J3QT65
ENSG00000144524ENST00000449174J3QT73
ENSG00000144524ENST00000449784J3KQV6
ENSG00000144524ENST00000450501J3QT66
ENSG00000144524ENST00000452375J3QT69
ENSG00000144524ENST00000611614A0A087X1P5
ENSG00000144524ENST00000620578Q9H9Q2
ENSG00000144524ENST00000620578A0A024R478
ENSG00000144524ENST00000631349J3QT66

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
DNA RepairREACTOMER-HSA-73894
Nucleotide Excision RepairREACTOMER-HSA-5696398
Global Genome Nucleotide Excision Repair (GG-NER)REACTOMER-HSA-5696399
DNA Damage Recognition in GG-NERREACTOMER-HSA-5696394
Transcription-Coupled Nucleotide Excision Repair (TC-NER)REACTOMER-HSA-6781827
Formation of TC-NER Pre-Incision ComplexREACTOMER-HSA-6781823
Clathrin-mediated endocytosisREACTOMER-HSA-8856828
Cargo recognition for clathrin-mediated endocytosisREACTOMER-HSA-8856825

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375609712023The IGF2BP3-COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression.2
375609712023The IGF2BP3-COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression.2
335034272021CSN7B defines a variant COP9 signalosome complex with distinct function in DNA damage response.4
335034272021CSN7B defines a variant COP9 signalosome complex with distinct function in DNA damage response.4

Citation

Dessen P

COPS7B (COP9 signalosome subunit 7B)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47495/img/favicon/teaching-explorer/