INO80C (INO80 complex subunit C)

2007-06-01  

Identity

HGNC
INO80C
LOCATION
18q12.2
LOCUSID
125476
ALIAS
C18orf37,IES6,hIes6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 125476
HGNC: 26994
Ensembl: ENSG00000153391

Variants:

dbSNP: 125476
ClinVar: 125476
TCGA: ENSG00000153391
COSMIC: INO80C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153391ENST00000334598Q6PI98
ENSG00000153391ENST00000441607Q6PI98
ENSG00000153391ENST00000586449K7ELX9
ENSG00000153391ENST00000586489K7EIY8
ENSG00000153391ENST00000587450K7ENM4
ENSG00000153391ENST00000589273K7EKI6
ENSG00000153391ENST00000590757K7EQ79
ENSG00000153391ENST00000591139M0R3E2
ENSG00000153391ENST00000592173Q6PI98

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DNA RepairREACTOMER-HSA-73894
Nucleotide Excision RepairREACTOMER-HSA-5696398
Global Genome Nucleotide Excision Repair (GG-NER)REACTOMER-HSA-5696399
DNA Damage Recognition in GG-NERREACTOMER-HSA-5696394
DeubiquitinationREACTOMER-HSA-5688426
UCH proteinasesREACTOMER-HSA-5689603

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
289547332017Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.59
289547332017Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.59
162303502005A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex.111
162303502005A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex.111

Citation

Dessen P

INO80C (INO80 complex subunit C)

Atlas Genet Cytogenet Oncol Haematol. 2007-06-01

Online version: http://atlasgeneticsoncology.org/gene/47570/gene-explorer/js/haematological-explorer/