FOXN3 (forkhead box N3)

2007-07-01  

Identity

HGNC
FOXN3
LOCATION
14q31.3
LOCUSID
1112
ALIAS
C14orf116,CHES1,PRO1635
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1112
MIM: 602628
HGNC: 1928
Ensembl: ENSG00000053254

Variants:

dbSNP: 1112
ClinVar: 1112
TCGA: ENSG00000053254
COSMIC: FOXN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000053254ENST00000261302O00409
ENSG00000053254ENST00000261302A0A024R6I1
ENSG00000053254ENST00000345097O00409
ENSG00000053254ENST00000345097A0A024R6I1
ENSG00000053254ENST00000553353H0YJY0
ENSG00000053254ENST00000553840H0YJ54
ENSG00000053254ENST00000553904G3V4N5
ENSG00000053254ENST00000554005H0YJ94
ENSG00000053254ENST00000555034G3V5C7
ENSG00000053254ENST00000555353O00409
ENSG00000053254ENST00000555855G3V3A7
ENSG00000053254ENST00000556916H0YJ22
ENSG00000053254ENST00000557258O00409
ENSG00000053254ENST00000557572H0YJ43
ENSG00000053254ENST00000557718H0YJG3
ENSG00000053254ENST00000615335O00409

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387188462024CHES1 modulated tumorigenesis and senescence of pancreas cancer cells through repressing AKR1B10.0
387188462024CHES1 modulated tumorigenesis and senescence of pancreas cancer cells through repressing AKR1B10.0
370161672023FOXN3 inhibits the progression of ovarian cancer through negatively regulating the expression of RPS15A.0
370161672023FOXN3 inhibits the progression of ovarian cancer through negatively regulating the expression of RPS15A.0
345114322021FOXN3 inhibits cell proliferation and invasion via modulating the AKT/MDM2/p53 axis in human glioma.5
345114322021FOXN3 inhibits cell proliferation and invasion via modulating the AKT/MDM2/p53 axis in human glioma.5
320782442020The clinical and prognostic significance of FOXN3 downregulation in acute myeloid leukaemia.3
322842512020MicroRNA-574-5p directly targets FOXN3 to mediate thyroid cancer progression via Wnt/β-catenin signaling pathway.10
326195842020FOXN3 suppresses the growth and invasion of papillary thyroid cancer through the inactivation of Wnt/β-catenin pathway.12
333174072020miR-574-5p Targets FOXN3 to Regulate the Invasion of Nasopharyngeal Carcinoma Cells via Wnt/β-Catenin Pathway.9
320782442020The clinical and prognostic significance of FOXN3 downregulation in acute myeloid leukaemia.3
322842512020MicroRNA-574-5p directly targets FOXN3 to mediate thyroid cancer progression via Wnt/β-catenin signaling pathway.10
326195842020FOXN3 suppresses the growth and invasion of papillary thyroid cancer through the inactivation of Wnt/β-catenin pathway.12
333174072020miR-574-5p Targets FOXN3 to Regulate the Invasion of Nasopharyngeal Carcinoma Cells via Wnt/β-Catenin Pathway.9
304838012019FOXN3 is downregulated in osteosarcoma and transcriptionally regulates SIRT6, and suppresses migration and invasion in osteosarcoma.4

Citation

Dessen P

FOXN3 (forkhead box N3)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47613/deep-insight-explorer/welcome