G3BP2 (G3BP stress granule assembly factor 2)

2007-08-01  

Identity

HGNC
LOCATION
4q21.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 9908
HGNC: 30291
Ensembl: ENSG00000138757

Variants:

dbSNP: 9908
ClinVar: 9908
TCGA: ENSG00000138757
COSMIC: G3BP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138757ENST00000357854Q9UN86
ENSG00000138757ENST00000357854A0A024RDB2
ENSG00000138757ENST00000359707Q9UN86
ENSG00000138757ENST00000359707A0A024RDE5
ENSG00000138757ENST00000395719Q9UN86
ENSG00000138757ENST00000395719A0A024RDE5
ENSG00000138757ENST00000499709D6R9X5
ENSG00000138757ENST00000503660D6RB17
ENSG00000138757ENST00000507252D6RBR0
ENSG00000138757ENST00000507745D6RAC7
ENSG00000138757ENST00000508510D6R9A4
ENSG00000138757ENST00000509100D6RGJ4
ENSG00000138757ENST00000509561D6RBM9
ENSG00000138757ENST00000510902H0YAE3
ENSG00000138757ENST00000511146D6RBW8
ENSG00000138757ENST00000511868D6REX8
ENSG00000138757ENST00000515457D6RE13

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386409832024Exosomal miRNA-92a derived from cancer-associated fibroblasts promote invasion and metastasis in breast cancer by regulating G3BP2.1
386409832024Exosomal miRNA-92a derived from cancer-associated fibroblasts promote invasion and metastasis in breast cancer by regulating G3BP2.1
368789032023USP7- and PRMT5-dependent G3BP2 stabilization drives de novo lipogenesis and tumorigenesis of HNSC.6
374610192023Chemotherapy-induced exosomal circBACH1 promotes breast cancer resistance and stemness via miR-217/G3BP2 signaling pathway.5
368789032023USP7- and PRMT5-dependent G3BP2 stabilization drives de novo lipogenesis and tumorigenesis of HNSC.6
374610192023Chemotherapy-induced exosomal circBACH1 promotes breast cancer resistance and stemness via miR-217/G3BP2 signaling pathway.5
357613862022EBF1-mediated up-regulation of lncRNA FGD5-AS1 facilitates osteosarcoma progression by regulating miR-124-3p/G3BP2 axis as a ceRNA.5
357613862022EBF1-mediated up-regulation of lncRNA FGD5-AS1 facilitates osteosarcoma progression by regulating miR-124-3p/G3BP2 axis as a ceRNA.5
334764862021BAALC-AS1/G3BP2/c-Myc feedback loop promotes cell proliferation in esophageal squamous cell carcinoma.11
334976112021G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.45
345170252021Genomics-guided targeting of stress granule proteins G3BP1/2 to inhibit SARS-CoV-2 propagation.10
345214232021MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer.23
334764862021BAALC-AS1/G3BP2/c-Myc feedback loop promotes cell proliferation in esophageal squamous cell carcinoma.11
334976112021G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.45
345170252021Genomics-guided targeting of stress granule proteins G3BP1/2 to inhibit SARS-CoV-2 propagation.10

Citation

Dessen P

G3BP2 (G3BP stress granule assembly factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-08-01

Online version: http://atlasgeneticsoncology.org/gene/47700/css/lib/teaching-explorer/deep-insight-explorer/