KRT13 (keratin 13)

2007-12-01  

Identity

HGNC
KRT13
LOCATION
17q21.2
LOCUSID
3860
ALIAS
CK13,K13,WSN2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3860
MIM: 148065
HGNC: 6415
Ensembl: ENSG00000171401

Variants:

dbSNP: 3860
ClinVar: 3860
TCGA: ENSG00000171401
COSMIC: KRT13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171401ENST00000246635P13646
ENSG00000171401ENST00000336861P13646
ENSG00000171401ENST00000464634K7EMJ2
ENSG00000171401ENST00000587435K7EQH6
ENSG00000171401ENST00000587544K7ERE3
ENSG00000171401ENST00000590425K7EMD9

Expression (GTEx)

0
5000
10000
15000
20000
25000
30000
35000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
KeratinizationREACTOMER-HSA-6805567

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
362696812023Cytokeratin 13 (CK13) expression in cancer: a tissue microarray study on 10,439 tumors.2
366107192023KRT13 is upregulated in pancreatic cancer stem-like cells and associated with radioresistance.1
381145322023KRT13 and UPK1B for differential diagnosis between metastatic lung carcinoma from oral squamous cell carcinoma and lung squamous cell carcinoma.0
362696812023Cytokeratin 13 (CK13) expression in cancer: a tissue microarray study on 10,439 tumors.2
366107192023KRT13 is upregulated in pancreatic cancer stem-like cells and associated with radioresistance.1
381145322023KRT13 and UPK1B for differential diagnosis between metastatic lung carcinoma from oral squamous cell carcinoma and lung squamous cell carcinoma.0
350785072022KRT13 promotes stemness and drives metastasis in breast cancer through a plakoglobin/c-Myc signaling pathway.18
350785072022KRT13 promotes stemness and drives metastasis in breast cancer through a plakoglobin/c-Myc signaling pathway.18
335379302021Enhanced KRT13 gene expression bestows radiation resistance in squamous cell carcinoma cells.3
343383862021Combined loss of expression of involucrin and cytokeratin 13 is associated with poor prognosis in squamous cell carcinoma of mobile tongue.7
335379302021Enhanced KRT13 gene expression bestows radiation resistance in squamous cell carcinoma cells.3
343383862021Combined loss of expression of involucrin and cytokeratin 13 is associated with poor prognosis in squamous cell carcinoma of mobile tongue.7
293260422018Keratin 13 gene is epigenetically suppressed during transforming growth factor-β1-induced epithelial-mesenchymal transition in a human keratinocyte cell line.11
294766682018Clinical features and molecular genetic analysis in a Turkish family with oral white sponge nevus.4
293260422018Keratin 13 gene is epigenetically suppressed during transforming growth factor-β1-induced epithelial-mesenchymal transition in a human keratinocyte cell line.11

Citation

Dessen P

KRT13 (keratin 13)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49870/gene-explorer/deep-insight-explorer/