MIRLET7A3 (microRNA let-7a-3)

2007-12-01  

Identity

HGNC
LOCATION
22q13.31
LOCUSID
ALIAS
LET7A3,MIRNLET7A3,let-7a-3

Other Information

Locus ID:

NCBI: 406883
MIM: 612143
HGNC: 31478
Ensembl: ENSG00000283990
miRBase:

Variants:

dbSNP: 406883
ClinVar: 406883
TCGA: ENSG00000283990
COSMIC: MIRLET7A3

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
346865052021Predictive Value of let-7a for Cancer Cell Repopulation between Chemotherapy and Long-Term Survival: A Prospective Study.2
346865052021Predictive Value of let-7a for Cancer Cell Repopulation between Chemotherapy and Long-Term Survival: A Prospective Study.2
322084172020Salivary microRNA miR-let-7a-5p and miR-3928 could be used as potential diagnostic bio-markers for head and neck squamous cell carcinoma.26
323457852020Let-7a-5p represses proliferation, migration, invasion and epithelial-mesenchymal transition by targeting Smad2 in TGF-b2-induced human lens epithelial cells.6
322084172020Salivary microRNA miR-let-7a-5p and miR-3928 could be used as potential diagnostic bio-markers for head and neck squamous cell carcinoma.26
323457852020Let-7a-5p represses proliferation, migration, invasion and epithelial-mesenchymal transition by targeting Smad2 in TGF-b2-induced human lens epithelial cells.6
312983822019Inhibition effect of exosomes-mediated Let-7a on the development and metastasis of triple negative breast cancer by down-regulating the expression of c-Myc.12
313300672019Let-7a-regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor.14
312983822019Inhibition effect of exosomes-mediated Let-7a on the development and metastasis of triple negative breast cancer by down-regulating the expression of c-Myc.12
313300672019Let-7a-regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor.14
304974742018Downregulation of exosomal let-7a-5p in dust exposed- workers contributes to lung cancer development.22
304974742018Downregulation of exosomal let-7a-5p in dust exposed- workers contributes to lung cancer development.22
272442252017Hypomethylation of let-7a-3 is associated with poor prognosis in myelodysplastic syndrome.8
272442252017Hypomethylation of let-7a-3 is associated with poor prognosis in myelodysplastic syndrome.8
262272202016Let-7a-3 hypomethylation is associated with favorable/intermediate karyotypes but not with survival in acute myeloid leukemia.3

Citation

Dessen P

MIRLET7A3 (microRNA let-7a-3)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49877/gene-fusions-explorer/favicon/manifest.json