CMTM5 (CKLF like MARVEL transmembrane domain containing 5)

2008-01-01  

Identity

HGNC
CMTM5
LOCATION
14q11.2
LOCUSID
116173
ALIAS
CKLFSF5

Other Information

Locus ID:

NCBI: 116173
MIM: 607888
HGNC: 19176
Ensembl: ENSG00000166091

Variants:

dbSNP: 116173
ClinVar: 116173
TCGA: ENSG00000166091
COSMIC: CMTM5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166091ENST00000339180Q96DZ9
ENSG00000166091ENST00000342473Q96DZ9
ENSG00000166091ENST00000359320Q96DZ9
ENSG00000166091ENST00000382809Q96DZ9
ENSG00000166091ENST00000397227Q96DZ9
ENSG00000166091ENST00000555731C9JAI6
ENSG00000166091ENST00000649278Q96DZ9

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
347915062022CMTM5 inhibits the development of prostate cancer via the EGFR/PI3K/AKT signaling pathway.3
347915062022CMTM5 inhibits the development of prostate cancer via the EGFR/PI3K/AKT signaling pathway.3
325681782020CMTM5/7 are biomarkers and prognostic factors in human breast carcinoma.6
330477192020[Association of CMTM5 gene expression with the risk of in-stent restenosis in patients with coronary artery disease after drug-eluting stent implantation and the effects and mechanisms of CMTM5 on human vascular endothelial cells].1
333313172020[Association between CMTM5 gene and coronary artery disease and the relative mechanism].1
325681782020CMTM5/7 are biomarkers and prognostic factors in human breast carcinoma.6
330477192020[Association of CMTM5 gene expression with the risk of in-stent restenosis in patients with coronary artery disease after drug-eluting stent implantation and the effects and mechanisms of CMTM5 on human vascular endothelial cells].1
333313172020[Association between CMTM5 gene and coronary artery disease and the relative mechanism].1
307042302019[Pathophysiologic mechanism of CMTM5 low expression in multiple myeloma progression].3
307042302019[Pathophysiologic mechanism of CMTM5 low expression in multiple myeloma progression].3
296919812018Up-regulation of miR-10b-3p promotes the progression of hepatocellular carcinoma cells via targeting CMTM5.17
296919812018Up-regulation of miR-10b-3p promotes the progression of hepatocellular carcinoma cells via targeting CMTM5.17
284579852017Validation of aspirin response-related transcripts in patients with coronary artery disease and preliminary investigation on CMTM5 function.9
284579852017Validation of aspirin response-related transcripts in patients with coronary artery disease and preliminary investigation on CMTM5 function.9
253875682015CMTM5 is reduced in prostate cancer and inhibits cancer cell growth in vitro and in vivo.23

Citation

Dessen P

CMTM5 (CKLF like MARVEL transmembrane domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2008-01-01

Online version: http://atlasgeneticsoncology.org/gene/49966/haematological-explorer/case-report-explorer/