UTS2R (urotensin 2 receptor)

2008-01-01  

Identity

HGNC
UTS2R
LOCATION
17q25.3
LOCUSID
2837
ALIAS
GPR14,UR-2-R,UTR,UTR2

Other Information

Locus ID:

NCBI: 2837
MIM: 600896
HGNC: 4468
Ensembl: ENSG00000181408

Variants:

dbSNP: 2837
ClinVar: 2837
TCGA: ENSG00000181408
COSMIC: UTS2R

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181408ENST00000313135Q9UKP6

Expression (GTEx)

0
1
2
3
4
5
6
7
8
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Neuroactive ligand-receptor interactionKEGGhsa04080
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

References

Pubmed IDYearTitleCitations
331562712021Novel Mutations in UTS2R are Associated with Adolescent Idiopathic Scoliosis in the Chinese Population.6
343893562021Lipidated peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as biased allosteric ligands.1
331562712021Novel Mutations in UTS2R are Associated with Adolescent Idiopathic Scoliosis in the Chinese Population.6
343893562021Lipidated peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as biased allosteric ligands.1
312931192020Urotensin II receptor expression in patients with ulcerative colitis: a pilot study.2
312931192020Urotensin II receptor expression in patients with ulcerative colitis: a pilot study.2
273387412017Urotensin-II Receptor: A Double Identity Receptor Involved in Vasoconstriction and in the Development of Digestive Tract Cancers and other Tumors.8
273387412017Urotensin-II Receptor: A Double Identity Receptor Involved in Vasoconstriction and in the Development of Digestive Tract Cancers and other Tumors.8
276001912016UII/GPR14 is involved in NF-κB-mediated colonic inflammation in vivo and in vitro.3
277154462016Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis.18
276001912016UII/GPR14 is involved in NF-κB-mediated colonic inflammation in vivo and in vitro.3
277154462016Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis.18
263818512015Urotensin II receptor on preoperative biopsy is associated with upstaging and upgrading in prostate cancer.12
263818512015Urotensin II receptor on preoperative biopsy is associated with upstaging and upgrading in prostate cancer.12
243573332014Urantide conformation and interaction with the urotensin-II receptor.2

Citation

Dessen P

UTS2R (urotensin 2 receptor)

Atlas Genet Cytogenet Oncol Haematol. 2008-01-01

Online version: http://atlasgeneticsoncology.org/gene/49974/tumors-explorer/teaching-explorer/