LGALS2 (galectin 2)

2008-01-01  

Identity

HGNC
LGALS2
LOCATION
22q13.1
LOCUSID
3957
ALIAS
HL14
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3957
MIM: 150571
HGNC: 6562
Ensembl: ENSG00000100079

Variants:

dbSNP: 3957
ClinVar: 3957
TCGA: ENSG00000100079
COSMIC: LGALS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100079ENST00000215886P05162
ENSG00000100079ENST00000416480B0QYC9

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
351638022022Regulatory T Cell Apoptosis during Preeclampsia May Be Prevented by Gal-2.5
351638022022Regulatory T Cell Apoptosis during Preeclampsia May Be Prevented by Gal-2.5
316087212021Syndecan 4, galectin 2, and death receptor 3 (DR3) as novel proteins in pathophysiology of preeclampsia.10
331102342021Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth.18
343712602021Gene polymorphisms of LGALS2, LGALS3 and LGALS9 in patients with rheumatoid arthritis.5
316087212021Syndecan 4, galectin 2, and death receptor 3 (DR3) as novel proteins in pathophysiology of preeclampsia.10
331102342021Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth.18
343712602021Gene polymorphisms of LGALS2, LGALS3 and LGALS9 in patients with rheumatoid arthritis.5
322443512020Placental Galectin-2 Expression in Gestational Diabetes: A Systematic, Histological Analysis.13
322443512020Placental Galectin-2 Expression in Gestational Diabetes: A Systematic, Histological Analysis.13
290937632017Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study.8
290937632017Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study.8
268855082016Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis.6
270705772016Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR).17
275630082016Human galectin-2 interacts with carbohydrates and peptides non-classically: new insight from X-ray crystallography and hemagglutination.11

Citation

Dessen P

LGALS2 (galectin 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-01-01

Online version: http://atlasgeneticsoncology.org/gene/49983/teaching-explorer/tumors-explorer/haematological-explorer/